在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Stress-70 protein, mitochondrial (Hspa9)

  • 中文名稱:
    小鼠Hspa9重組蛋白
  • 貨號:
    CSB-YP010830MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Hspa9重組蛋白
  • 貨號:
    CSB-EP010830MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Hspa9重組蛋白
  • 貨號:
    CSB-EP010830MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Hspa9重組蛋白
  • 貨號:
    CSB-BP010830MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Hspa9重組蛋白
  • 貨號:
    CSB-MP010830MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Hspa9; Grp75; Hsp74; Hspa9aStress-70 protein; mitochondrial; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; Peptide-binding protein 74; PBP74; p66 MOT
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    47-679
  • 氨基酸序列
    ASEA IKGAVVGIDL GTTNSCVAVM EGKQAKVLEN AEGARTTPSV VAFTADGERL VGMPAKRQAV TNPNNTFYAT KRLIGRRYDD PEVQKDTKNV PFKIVRASNG DAWVEAHGKL YSPSQIGAFV LMKMKETAEN YLGHTAKNAV ITVPAYFNDS QRQATKDAGQ ISGLNVLRVI NEPTAAALAY GLDKSEDKVI AVYDLGGGTF DISILEIQKG VFEVKSTNGD TFLGGEDFDQ ALLRHIVKEF KRETGVDLTK DNMALQRVRE AAEKAKCELS SSVQTDINLP YLTMDASGPK HLNMKLTRAQ FEGIVTDLIK RTIAPCQKAM QDAEVSKSDI GEVILVGGMT RMPKVQQTVQ DLFGRAPSKA VNPDEAVAIG AAIQGGVLAG DVTDVLLLDV TPLSLGIETL GGVFTKLINR NTTIPTKKSQ VFSTAADGQT QVEIKVCQGE REMAGDNKLL GQFTLIGIPP APRGVPQIEV TFDIDANGIV HVSAKDKGTG REQQIVIQSS GGLSKDDIEN MVKNAEKYAE EDRRKKERVE AVNMAEGIIH DTETKMEEFK DQLPADECNK LKEEISKMRA LLAGKDSETG ENIRQAASSL QQASLKLFEM AYKKMASERE GSGSSGTGEQ KEDQKEEKQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging.
  • 基因功能參考文獻:
    1. Thus Hspa9 regulates erythroid differentiation through ISC cluster assembly, providing a pathophysiological mechanism for an MDS subtype characterized by HSPA9 haploinsufficiency PMID: 26702583
    2. This study demonstred that Mortalin expression in brain astrocytes. PMID: 26095919
    3. data imply a role for Hspa9 in B lymphopoiesis and Stat5 activation downstream of IL-7 signaling PMID: 25550197
    4. down-regulation of mortalin may potentiate Abeta-mediated mitochondrial fragmentation and dysfunction in AD. PMID: 24324263
    5. the mortalin/DJ-1 complex guards against mitochondrial oxidative stress and is indispensable for the maintenance of hematopoietic stem cells PMID: 24243970
    6. Inflammatory response of microglial cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin. PMID: 23395614
    7. Knockdown of Hspa9 results in a decrease in hematopoietic progenitors resulting in myelodysplastic syndromes. PMID: 21123823
    8. Data show that RNAi-mediated down-regulation of GRP75 and GRP75-blocking antibodies, both of which inhibited macromolecular endocytosis. PMID: 20624969
    9. The asymmetric segregation of mortalin in the bipotent cell line and its uniform distribution in a committed, lineage-restricted cell line raises the possibility that it may play a role in cell fate determination PMID: 11850063
    10. Mortalin imaging was used in normal and cancer cells with quantum dotimmuno-conjugates. PMID: 14728808
    11. We propose that the differential regulation of mortalin in AD and by the APOE genotype is a cellular defense mechanism responding to increases in oxidative stress. PMID: 17050040

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion. Nucleus, nucleolus.
  • 蛋白家族:
    Heat shock protein 70 family
  • 組織特異性:
    Found in all the cell types examined.
  • 數據庫鏈接:


主站蜘蛛池模板: 国产av丝袜一区二区三区| 少妇人妻无码专区在线视频| 97无码免费人妻超级碰碰碰碰| 久久精品免费一区二区三区| 日本丶国产丶欧美色综合| 丰满人妻被黑人猛烈进入| 波多野结衣在线播放| 国内少妇偷人精品免费| 五月丁香综合缴情六月小说| 少妇和邻居做不戴套视频| 久久精品人人做人人爽97| 国产成人久久777777| 亚洲人成电影网站色www两男一女| 黑人粗长大战亚洲女| 亚洲成aⅴ人片久青草影院| 天天摸天天做天天爽天天弄| 国内午夜熟妇又乱又伦| 国产涩涩视频在线观看| 解开人妻的裙子猛烈进入| 亚洲午夜无码久久久久蜜臀av| 久久久久99精品成人品| 免费看成人毛片无码视频| 东京热加勒比无码少妇| 成人性生交片无码免费看| 日本五月天婷久久网站| 国产亚洲精品久久久久久入口| 中文字字幕在线精品乱码 | 极品少妇被猛得白浆直流草莓视频| 欧美 日韩 人妻 高清 中文| 欧美一性一乱一交一视频| 久久精品高清一区二区三区 | 天天摸夜夜添狠狠添婷婷| 亚洲精品无码一区二区| 国产亚洲精久久久久久无码77777 国产中年熟女高潮大集合 | 亚洲在线国产日韩欧美| 精品久久久久久久久午夜福利| 国产1卡二卡3卡四卡乱码视频| 狠狠色噜噜狠狠狠狠7777米奇| 99久久久无码国产精品免费 | 国产精品无码av不卡顿| 日日摸天天爽天天爽视频|