在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Src-like-adapter (Sla)

Recombinant Mouse Src-like-adapter (Sla)

  • 中文名稱：
    小鼠Sla重組蛋白
  • 貨號：
    CSB-YP736755MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sla重組蛋白
  • 貨號：
    CSB-EP736755MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sla重組蛋白
  • 貨號：
    CSB-EP736755MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sla重組蛋白
  • 貨號：
    CSB-BP736755MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sla重組蛋白
  • 貨號：
    CSB-MP736755MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sla
  • Uniprot No.：
  • 別名：
    Sla; Slap; Slap1; Src-like-adapter; Src-like-adapter protein 1; SLAP-1; mSLAP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-281
  • 氨基酸序列
    GNSMKSTSP PSERPLSSSE GLESDFLAVL TDYPSPDISP PIFRRGEKLR VISDEGGWWK AISLSTGRES YIPGICVARV YHGWLFEGLG RDKAEELLQL PDTKIGSFMI RESETKKGFY SLSVRHRQVK HYRIFRLPNN WYYISPRLTF QCLEDLVTHY SEVADGLCCV LTTPCLAQNI PAPTSHPSPC TSPGSPVTLR QKTFDWKRVS RLQEGSEGAE NPLRVDESLF SYGLRESIAS YLSLTGDDSS SFDRKKKSLS LMYTGSKRKS SFFSAPQYFE D
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
  • 基因功能參考文獻：
    1. SLAP and SLAP2 are critical inhibitors of platelet (hem)ITAM signaling in the setting of arterial thrombosis and ischemic stroke PMID: 25301707
    2. SLAP is a critical regulator of B-cell development and function and its deficiency leads to decreased autoreactive B cells that are otherwise maintained by inefficient receptor editing or failed negative selection. PMID: 24440645
    3. Src-like adaptor protein (SLAP) functions as a negative regulator of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) generation of monocyte-derived dendritic cells of bone marrow origin. PMID: 21220694
    4. SLAP deficiency dramatically reduces both the incidence and severity of arthritis and prevents development of chronic arthritis in the double SKG (mutant ZAP70) Src-like adapter protein (SLAP) knockout mouse model. PMID: 21248251
    5. SLAP negatively regulates differentiation of osteoclasts and proliferation of their precursors. PMID: 20225239
    6. SLAP functions in a pathway that requires the phosphorylated TCRzeta chain and the Src family kinase Lck, but not ZAP-70 (zeta-associated protein of 70 kD). PMID: 16027224
    7. SLAP has a conserved function in B and T cells by adapting c-Cbl to the antigen-receptor complex and targeting it for degradation PMID: 17110436

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endosome. Note=Colocalizes with endosomes.
  • 組織特異性：
    Predominantly expressed in lymphoid tissues. Highly expressed in spleen, thymus and lymph nodes. Weakly expressed in lung and brain. Expressed in T-cells and at low level in B-cells.
  • 數據庫鏈接：

    KEGG: mmu:20491

    STRING: 10090.ENSMUSP00000131865

    UniGene: Mm.7601



主站蜘蛛池模板： 免费不卡无码av在线观看| 曰本无码不卡高清av一二 | 欧美丰满熟妇xxxx性ppx人交 | 大学生久久香蕉国产线看观看| 亚洲欧洲无码av电影在线观看| 2020精品国产视| 无码视频免费一区二区三区| 亚洲精品久久久久中文字幕| 妺妺窝人体色www聚色窝仙踪| 国产av激情久久无码天堂 | 国产毛片一区二区精品| 少妇人妻无码专区毛片| 免费国偷自产拍精品视频 | 激情毛片无码专区| 亚洲乱码卡一卡二卡| 国产三级在线观看播放视频| 中国女人做爰视频| 国产免费无码一区二区| 人妻丰满熟妇a无码区| 日本熟妇厨房bbw| 男女做爰猛烈叫床视频免费| 久在线精品视频线观看| 亚洲精品久久66国产高清| 国产欧美成人一区二区a片| 国内精品免费久久久久电影院| 性欧美疯狂xxxxbbbb| 婷婷激情综合色五月久久竹菊影视 | 中国女人大白屁股ass| 亚洲中文字幕第一页在线| 拍真实国产伦偷精品| 日本十八禁视频无遮挡| 久久久国产99久久国产久麻豆| 偷拍农村老熟妇xxxxx7视频 | 久久久久久亚洲综合影院| 人妻无码第一区二区三区| 男人女人午夜视频免费| 色舞月亚洲综合一区二区| 亚洲精品一区久久久久久| 久久777国产线看观看精品 | 国产欧洲精品自在自线官方| 久久精品无码一区二区三区免费|