在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Src kinase-associated phosphoprotein 2 (Skap2)

Recombinant Mouse Src kinase-associated phosphoprotein 2 (Skap2)

  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-YP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-EP661048MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-EP661048MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-BP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-MP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Skap2
  • Uniprot No.：
  • 別名：
    Skap2; Prap; Ra70; Saps; Scap2; Skap55r; Src kinase-associated phosphoprotein 2; Pyk2/RAFTK-associated protein; SKAP55 homolog; SKAP-HOM; Src family-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; Src-associated adapter protein with PH and SH3 domains
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-358
  • 氨基酸序列
    MPNPSCTSSP GPLPEEIRNL LADVETFVAD TLKGENLSKK AKEKRESLIK KIKDVKSVYL QEFQDKGDAE DGDEYDDPFA GPADTISLAS ERYDKDDDGP SDGNQFPPIA AQDLPFVIKA GYLEKRRKDH SFLGFEWQKR WCALSKTVFY YYGSDKDKQQ KGEFAIDGYD VRMNNTLRKD GKKDCCFEIC APDKRIYQFT AASPKDAEEW VQQLKFILQD LGSDVIPEDD EERGELYDDV DHPAAVSSPQ RSQPIDDEIY EELPEEEEDT ASVKMDEQGK GSRDSVHHTS GDKSTDYANF YQGLWDCTGA LSDELSFKRG DVIYILSKEY NRYGWWVGEM KGAIGLVPKA YLMEMYDI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
  • 基因功能參考文獻：
    1. Skap2 is essential to activate the beta2 integrins, and loss of Skap2 function is sufficient to cause a leukocyte adhesion deficiency (LAD)-like phenotype in mice. PMID: 28183734
    2. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs. PMID: 26577701
    3. RA70/Scap2 may be necessary for RA-induced neuronal differentiation from the posterior neuroectoderm. PMID: 24846415
    4. a novel role of SKAP-Hom and its phosphorylation in the regulation of cellular motility. PMID: 23897807
    5. Sirpalpha is not exclusively immunoinhibitory, and illuminate previously unexplained observations implicating Skap2 and Sirpalpha in mouse models of inflammatory disease. PMID: 22976304
    6. M-CSF receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin PMID: 15894167
    7. SKAP-HOM is required for proper activation of the immune system, likely by regulating the cross-talk between immunoreceptors and integrins. PMID: 16135797
    8. Results describe a link between ADAP/SKAP-55 and the Rap1/RIAM complex and provide a potential new mechanism for T cell receptor-mediated integrin activation. PMID: 17403904
    9. SKAP-HOM expression in DCs is required for the induction of an optimal immune response; antigen-dependent conjugate formed between wild-type T cells and SKAP-HOM(-/-) DCs is delayed PMID: 19369640

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=Membrane ruffles of macrophages. Perikarya and dendrites from neurons.
  • 蛋白家族：
    SKAP family
  • 組織特異性：
    Expressed in kidney, lung, liver, spleen, bone marrow and testis. Present in T-cells, B-cells, and all cells of the myelomonocytic lineage. Present in all brain regions, with highest levels in neurons from the Purkinje cell layer, hippocampal gyrus, corte
  • 數據庫鏈接：


主站蜘蛛池模板： 久久久久久久岛国免费观看| 免费人成又黄又爽的视频| 18禁超污无遮挡无码网址| 日本乱亲伦视频中文字幕| 成人黄网站高清免费视频 | 久久综合亚洲色hezyo社区| 日本极品少妇xxxx| 国产午夜大地久久| 成人亚欧欧美激情在线观看| 牲高潮99爽久久久久777| 久久精品久久久久观看99水蜜桃| 巨胸不知火舞露双奶头无遮挡| 国产sm主人调教女m视频| 国产丝袜无码一区二区视频| 中日韩精品卡一卡二卡3卡| 亚洲欧美中文日韩v在线97| 狠狠躁18三区二区一区ai明星| 精品无码国产一区二区三区51安| 精品爆乳一区二区三区无码av| 亚洲 欧美 另类图片| 国产精品亚洲а∨怡红院| 日日噜噜夜夜狠狠va视频| 在线观看免费人成视频| 日本精品少妇一区二区三区| 亚洲精品国产熟女久久久| 97se狠狠狠狠狼鲁亚洲综合色| 国模小黎自慰337p人体| 又粗又黑又大的吊av| 欧美大屁股xxxxhd黑色| 韩国午夜福利片在线观看| 亚洲性色av性色在线观看| 任我爽橹在线视频精品583| 天堂www中文在线资源| 成人免费看www网址入口| 亚洲日韩性欧美中文字幕| 亚洲精品少妇高清30p| 国产精品久久久久久久久久免费看| 亚洲欧美一区二区三区日产| 在线观看无码不卡av中文| 999成人精品视频在线| 亚洲人成网7777777国产|