在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Src kinase-associated phosphoprotein 2 (Skap2)

Recombinant Mouse Src kinase-associated phosphoprotein 2 (Skap2)

  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-YP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-EP661048MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-EP661048MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-BP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Skap2重組蛋白
  • 貨號：
    CSB-MP661048MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Skap2
  • Uniprot No.：
  • 別名：
    Skap2; Prap; Ra70; Saps; Scap2; Skap55r; Src kinase-associated phosphoprotein 2; Pyk2/RAFTK-associated protein; SKAP55 homolog; SKAP-HOM; Src family-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; Src-associated adapter protein with PH and SH3 domains
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-358
  • 氨基酸序列
    MPNPSCTSSP GPLPEEIRNL LADVETFVAD TLKGENLSKK AKEKRESLIK KIKDVKSVYL QEFQDKGDAE DGDEYDDPFA GPADTISLAS ERYDKDDDGP SDGNQFPPIA AQDLPFVIKA GYLEKRRKDH SFLGFEWQKR WCALSKTVFY YYGSDKDKQQ KGEFAIDGYD VRMNNTLRKD GKKDCCFEIC APDKRIYQFT AASPKDAEEW VQQLKFILQD LGSDVIPEDD EERGELYDDV DHPAAVSSPQ RSQPIDDEIY EELPEEEEDT ASVKMDEQGK GSRDSVHHTS GDKSTDYANF YQGLWDCTGA LSDELSFKRG DVIYILSKEY NRYGWWVGEM KGAIGLVPKA YLMEMYDI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
  • 基因功能參考文獻：
    1. Skap2 is essential to activate the beta2 integrins, and loss of Skap2 function is sufficient to cause a leukocyte adhesion deficiency (LAD)-like phenotype in mice. PMID: 28183734
    2. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs. PMID: 26577701
    3. RA70/Scap2 may be necessary for RA-induced neuronal differentiation from the posterior neuroectoderm. PMID: 24846415
    4. a novel role of SKAP-Hom and its phosphorylation in the regulation of cellular motility. PMID: 23897807
    5. Sirpalpha is not exclusively immunoinhibitory, and illuminate previously unexplained observations implicating Skap2 and Sirpalpha in mouse models of inflammatory disease. PMID: 22976304
    6. M-CSF receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin PMID: 15894167
    7. SKAP-HOM is required for proper activation of the immune system, likely by regulating the cross-talk between immunoreceptors and integrins. PMID: 16135797
    8. Results describe a link between ADAP/SKAP-55 and the Rap1/RIAM complex and provide a potential new mechanism for T cell receptor-mediated integrin activation. PMID: 17403904
    9. SKAP-HOM expression in DCs is required for the induction of an optimal immune response; antigen-dependent conjugate formed between wild-type T cells and SKAP-HOM(-/-) DCs is delayed PMID: 19369640

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=Membrane ruffles of macrophages. Perikarya and dendrites from neurons.
  • 蛋白家族：
    SKAP family
  • 組織特異性：
    Expressed in kidney, lung, liver, spleen, bone marrow and testis. Present in T-cells, B-cells, and all cells of the myelomonocytic lineage. Present in all brain regions, with highest levels in neurons from the Purkinje cell layer, hippocampal gyrus, corte
  • 數據庫鏈接：


主站蜘蛛池模板： 国产最新精品自产在线观看| 久久99国产精品久久99| 国产麻豆精品福利在线观看| 久久久99久久久国产自输拍| 国产精品第12页| 窝窝午夜看片| 在线看免费无码av天堂| 精品国产乱码久久久久软件 | 色夜码无码av网站| 51国产偷自视频区视频| 精品无码三级在线观看视频| 免费又黄又裸乳的视频| 亚洲制服有码在线丝袜| 午夜国产亚洲精品一区 | 色窝窝免费一区二区三区| 一二三四免费观看在线视频中文版| 亚洲精品专区在线观看| 午夜福利不卡在线视频| 国产美女精品视频线免费播放软件| 国产草草影院ccyycom| 五月婷婷开心中文字幕| 日韩欧美一中文字暮专区| 亚洲精品av一二三区无码| 国产成人精品s8视频| 亚洲午夜成人片| 亚洲午夜性猛春交xxxx| 粗壮挺进人妻水蜜桃成熟漫画| 丰满人妻熟妇乱又伦精品app| 加勒比东京热无码一区| 亚洲精华国产精华精华液网站 | 午夜福利片手机在线播放| 秋霞在线观看片无码免费不卡| 亚洲精品乱码久久久久久按摩| 精品国产成人亚洲午夜福利| 2020精品自拍视频曝光| 亚洲国产成人久久综合一区77| 暴力调教一区二区三区| 狂野欧美性猛交免费视频| 国产丝袜无码一区二区视频| 性无码专区一色吊丝中文字幕| 无码乱码av天堂一区二区|