在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Sphingosine 1-phosphate receptor 5 (S1pr5), partial

  • 中文名稱:
    小鼠S1pr5重組蛋白
  • 貨號:
    CSB-YP838693MO1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠S1pr5重組蛋白
  • 貨號:
    CSB-EP838693MO1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠S1pr5重組蛋白
  • 貨號:
    CSB-EP838693MO1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠S1pr5重組蛋白
  • 貨號:
    CSB-BP838693MO1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠S1pr5重組蛋白
  • 貨號:
    CSB-MP838693MO1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    S1pr5; Edg8; Lpb4; Sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P5; Endothelial differentiation G-protein-coupled receptor 8; Lysophospholipid receptor B4; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. S1P activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival. S1P activation on O4-positive pre-oligodendrocytes induces process retraction via a Rho kinase/collapsin response-mediated protein signaling pathway. The S1P-induced survival of mature oligodendrocytes is mediated through a pertussis toxin-sensitive, Akt-dependent pathway. S1P activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival. These effects depend on the developmental stage of the cell.
  • 基因功能參考文獻:
    1. reduced frequency of patrolling monocytes in bone marrow of KO mice PMID: 23519784
    2. Coordinated changes in CXCR4 and S1P5 responsiveness govern NK-cell trafficking. PMID: 21911833
    3. Fndings suggest that S1P(5) may mediate the effects of S1P in terms of regulating ERK-1/2 signaling in ES cells. PMID: 19228106
    4. The molecular identity, functional properties, and expression profile of the S1P5 (Edg-8) receptor have been characterized. PMID: 11705398
    5. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. PMID: 11967257
    6. Edg8/S1P5 activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival and that these effects depend on the developmental stage of the cell. PMID: 15703400
    7. Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells. PMID: 16116177
    8. KLF2 regulates T cell homeostasis at least partly by controlling CD62L and S1P1 expression, and therefore T cell egress from the thymus and circulation in the periphery. PMID: 17548599
    9. These findings identify S1P5 as a T-bet-induced gene that is required for natural killer cell egress from lymph nodes and bone marrow. PMID: 19808259

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in spleen and brain. In the CNS expression is restricted to oligodendrocytes.
  • 數據庫鏈接:


主站蜘蛛池模板: 在线视频国产网址你懂的| 激情综合婷婷丁香五月蜜桃| 亚洲精品国产高清在线观看| 十八禁无码免费网站| 亚洲女人被黑人巨大进入| 日日噜噜夜夜爽爽| 成人免费看www网址入口 | 国产人妻精品久久久久野外| 久久午夜夜伦鲁鲁片无码免费| 亚洲aⅴ永久无码一区二区三区 | 又色又爽又黄又无遮挡的网站| 超碰97久久国产精品牛牛| 色鬼7777久久| 国产精品成人无码久久久| 卡1卡2卡3精品接入口| 日韩精品无码去免费专区| 亚洲精品一区二三区不卡| 亚洲妓女综合网99| 玩弄漂亮少妇高潮白浆| 四川骚妇无套内射舔了更爽| 免费国产线观看免费观看| 三个男吃我奶头一边一个视频 | 精品四虎国产在免费观看| 热99re久久精品这里都是精品免费 | 欧美成年视频在线观看| 亚洲va无码专区国产乱码| 无码国产精品高清免费| 久久青青草原精品国产| 亚洲第一女人av| 国产欧美日韩综合视频专区| 亚洲亚洲人成无码网www| 国语自产精品视频在线第100页| 丰满少妇被猛烈进入无码| 国产69精品久久久久777| 久久精品国产亚洲欧美成人| 欧美日韩精品一区二区在线视频| 丰满人妻在公车被猛烈进入电影| xx性欧美肥妇精品久久久久久| 国产voyeur精品偷窥222| 亚洲 欧美精品suv| 国产日产久久高清欧美一区 |