在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Spermine oxidase (Smox)

In Stock
  • 中文名稱:
    小鼠Smox重組蛋白
  • 品名簡稱:
    Recombinant Mouse Smox protein
  • 貨號:
    CSB-EP021844MOc7
  • 說明書:
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    Polyamine oxidase 1;PAO-1;PAOh1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    68.8 kDa
  • 表達區(qū)域:
    1-555aa
  • 氨基酸序列
    MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGCRIPKDVVEEFSDLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEPRGEGDHNHDTGEGGQSGENPQQGRWDEDEPWPVVVECEDCEVIPADHVIVTVSLGVLKRQYTSFFRPCLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESCTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
  • 基因功能參考文獻:
    1. Novel evidences of the complex and critical functions carried out by spermine oxidase and spermine in the mammalian brain. PMID: 23840306
    2. Spermine oxidase is an important regulator of muscle gene expression and fiber size. PMID: 25406264
    3. Data (including data from studies using recombinant mutant proteins) suggest that Glu216-Ser218 is a hot spot responsible for Smox substrate specificity; Smox with mutation E216L/S218A exhibits specificity for N'-acetylspermine rather than spermine. PMID: 24854736
    4. ROS overexposure by mSMOX delivers an earlier adaptive response to radiation PMID: 23857253
    5. Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA. PMID: 21839041
    6. Spermine oxidase binds spermine in a similar conformation as that observed in the yeast polyamine oxidase FMS1-spermine complex and demonstrate a major role for residues His82 and Lys367 in substrate binding and catalysis. PMID: 20839014
    7. expression and characterization of mouse spermine oxidase PMID: 12458219
    8. we identified a second domain that is necessary for nuclear localization of the spermine oxidase splice variant PMID: 15955064

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.; [Isoform 2]: Cytoplasm. Nucleus.
  • 蛋白家族:
    Flavin monoamine oxidase family
  • 組織特異性:
    Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
  • 數(shù)據(jù)庫鏈接:

    KEGG: mmu:228608

    UniGene: Mm.136586



主站蜘蛛池模板: 国产精品原创巨作av| 欧美成 人 网 站 免费| 人妻少妇精品无码专区app| 日产一区日产2区| 蜜桃av无码免费看永久| 国产爆乳无码视频在线观看3| 国产精品成人久久电影| 国产粉嫩小泬在线观看泬 | 色噜噜狠狠成人中文综合| 久久av无码精品人妻糸列| 女人被狂躁到高潮视频免费软件| 一本一道av中文字幕无码| 无码人妻久久一区二区三区app | 精品无码国产自产在线观看水浒传| 沈阳45老熟女高潮喷水亮点| 真人祼交二十三式视频| 女人的天堂a国产在线观看| 色优久久久久综合网鬼色| 欧美另类videosbestsex日本| 中日韩高清无专码区2021| 欧亚乱熟女一区二区三区在线| 亚洲.欧美.在线视频| 色狠狠成人综合网| 欧美性开放情侣网站| 成人做受视频试看120秒| 久爱无码免费视频在线| 真人抽搐一进一出视频| 日韩人妻无码精品免费shipin| 国产成人亚洲精品另类动态| 国产无遮挡又黄又爽动态图| 欧美 日韩版国产在线播放| 欧美性白人极品hd| 日本欧美久久久久免费播放网| 国产在线看片免费观看| 五十路熟妇高熟无码视频| 大地资源在线播放观看mv| 亚洲精品无码av黄瓜影视| 国产亚洲aⅴ在线电影| 精品一区二区三区四区五区六区| 人人做人人爽人人爱| 两个美女裸体舌吻互扒内裤|