在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Spermine oxidase (Smox)

  • 中文名稱:
    小鼠Smox重組蛋白
  • 貨號:
    CSB-BP021844MO
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Smox重組蛋白
  • 貨號:
    CSB-EP021844MO-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Smox重組蛋白
  • 貨號:
    CSB-MP021844MO
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Name:Smox Synonyms:Smo
  • Uniprot No.:
  • 別名:
    Smox; SmoSpermine oxidase; EC 1.5.3.16; Polyamine oxidase 1; PAO-1; PAOh1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-555
  • 氨基酸序列
    MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA RALLEQGFTD VTVLEASSHI GGRVQSVRLG DTTFELGATW IHGSHGNPIY QLAEANGLLE ETTDGERSVG RISLYSKNGV ACYLTNRGCR IPKDVVEEFS DLYNEVYNMT QEFFRHGKPV NAESQNSVGV FTREKVRNRI RDDPDDTEAT KRLKLAMIQQ YLKVESCESS SHSIDEVSLS AFGEWTEIPG AHHIIPSGFM RVVELLAEGI PPHVIQLGKP VRCIHWDQAS AHPRGPEIEP RGEGDHNHDT GEGGQSGENP QQGRWDEDEP WPVVVECEDC EVIPADHVIV TVSLGVLKRQ YTSFFRPCLP TEKVAAIHRL GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESCTLTYP PELWYRKICG FDVLYPPERY GHVLSGWICG EEALVMERCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA ARLIEMYRDL FQQGP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
  • 基因功能參考文獻:
    1. Novel evidences of the complex and critical functions carried out by spermine oxidase and spermine in the mammalian brain. PMID: 23840306
    2. Spermine oxidase is an important regulator of muscle gene expression and fiber size. PMID: 25406264
    3. Data (including data from studies using recombinant mutant proteins) suggest that Glu216-Ser218 is a hot spot responsible for Smox substrate specificity; Smox with mutation E216L/S218A exhibits specificity for N'-acetylspermine rather than spermine. PMID: 24854736
    4. ROS overexposure by mSMOX delivers an earlier adaptive response to radiation PMID: 23857253
    5. Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA. PMID: 21839041
    6. Spermine oxidase binds spermine in a similar conformation as that observed in the yeast polyamine oxidase FMS1-spermine complex and demonstrate a major role for residues His82 and Lys367 in substrate binding and catalysis. PMID: 20839014
    7. expression and characterization of mouse spermine oxidase PMID: 12458219
    8. we identified a second domain that is necessary for nuclear localization of the spermine oxidase splice variant PMID: 15955064

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.; [Isoform 2]: Cytoplasm. Nucleus.
  • 蛋白家族:
    Flavin monoamine oxidase family
  • 組織特異性:
    Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.
  • 數據庫鏈接:

    KEGG: mmu:228608

    UniGene: Mm.136586



主站蜘蛛池模板: 亚洲日韩乱码中文字幕| 狠狠躁夜夜躁人人爽天天5| 熟妇人妻久久中文字幕| 国产精品一区二区香蕉| 日本丰满熟妇bbxbbxhd| 人人妻人人爽人人做夜欢视频九色| 亚洲午夜精品a片一区二区app| 一本久道中文无码字幕av| 国产熟睡乱子伦视频| 成人动漫在线观看| 国产在线精品99一卡2卡| 日本妇人成熟免费中文字幕| 尹人香蕉99久久综合网站| 国产香蕉97碰碰久久人人| 男女猛烈xx00免费视频试看| 午夜精品久久久内射近拍高清| 99久久无色码中文字幕人妻| 色婷婷五月综合色啪网| 无码国内精品人妻少妇蜜桃视频| 婷婷无套内射影院| 国产清纯在线一区二区www| 色天使久久综合给合久久97色| 国产精品va无码免费| 大肉大捧一进一出视频| 久久本色成人综合网| 国产精品无码av不卡顿| 亚洲精品成a人在线观看 | 亚洲精品国产电影| 尤物av无码国产在线看| 人妻aⅴ中文字幕无码| 欧美亚洲国产一区二区三区| 中文人妻无码一区二区三区信息| 色丁狠狠桃花久久综合网| 国产国拍精品av在线观看按摩 | 国产手机在线αⅴ片无码观看| 色多多www视频在线观看免费| 亚洲欧美中文字幕日韩一区二区| 色婷婷香蕉在线一区二区| 久久久国产精品消防器材| 欧美成人精品福利视频| 少妇呻吟白浆高潮啪啪69 |