在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Serine/threonine-protein kinase pim-3 (Pim3)

Recombinant Mouse Serine/threonine-protein kinase pim-3 (Pim3)

  • 中文名稱：
    小鼠Pim3重組蛋白
  • 貨號：
    CSB-YP018014MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Pim3重組蛋白
  • 貨號：
    CSB-EP018014MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Pim3重組蛋白
  • 貨號：
    CSB-EP018014MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Pim3重組蛋白
  • 貨號：
    CSB-BP018014MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Pim3重組蛋白
  • 貨號：
    CSB-MP018014MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Pim3
  • Uniprot No.：
  • 別名：
    Pim3; Serine/threonine-protein kinase pim-3; EC 2.7.11.1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-326
  • 氨基酸序列
    MLLSKFGSLA HLCGPGGVDH LPVKILQPAK ADKESFEKVY QVGAVLGSGG FGTVYAGSRI ADGLPVAVKH VVKERVTEWG SLGGVAVPLE VVLLRKVGAA GGARGVIRLL DWFERPDGFL LVLERPEPAQ DLFDFITERG ALDEPLARRF FAQVLAAVRH CHNCGVVHRD IKDENLLVDL RSGELKLIDF GSGAVLKDTV YTDFDGTRVY SPPEWIRYHR YHGRSATVWS LGVLLYDMVC GDIPFEQDEE ILRGRLFFRR RVSPECQQLI EWCLSLRPSE RPSLDQIAAH PWMLGTEGSV PENCDLRLCA LDTDDGASTT SSSESL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression and protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
  • 基因功能參考文獻：
    1. Loss of PIM3 is associated with abnormal hematopoietic phenotypes. PMID: 23360755
    2. investigation of physiological role of Pim3 in beta-cell function: regulates glucose-stimulated insulin secretion; limits ERK signaling; interacts with SOCS6; Pim3 localized to beta-cell; Pim3 knockout mice display increased glucose tolerance PMID: 21099329
    3. Pim-3 has an important role in modulating c-Myc and PGC-1alpha protein levels and cell growth PMID: 21187426
    4. All three Pim kinase family members predominantly phosphorylate Bad on Ser112 and in addition are capable of phosphorylating Bad on multiple sites associated with the inhibition of the pro-apoptotic function of Bad in HEK-293 cells PMID: 16403219
    5. Pim-3 kinase has a novel role in the control of self-renewal of embryonic stem cells. PMID: 17717068
    6. Pim-3 is expressed in endothelial cells and promotes vascular tube formation. PMID: 19229879

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily
  • 組織特異性：
    Detected in pancreas but exclusively in beta-cells.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲日韩乱码一区二区三区四区| 成人免费播放视频777777| 人人妻人人澡人人爽精品日本| 精品人伦一区二区三区蜜桃免费 | 欧美交换国产一区内射| 高中生自慰www网站| 国产精品高潮呻吟av久久无吗| 国产好吊看视频在线观看| 午夜激成人免费视频在线观看| 午夜精品久久久久久毛片| 日韩精品无码一区二区| 亚洲欧美人成网站在线观看看| 天堂中文在线最新版地址| 国产成a人亚洲精品无码久久网| 中国国产野外1级毛片视频| 麻豆专媒体一区二区| 午夜dv内射一区二区| 好男人www社区| 亚洲综合色噜噜狠狠网站超清| 高中国产开嫩苞实拍视频在线观看 | 国产超薄肉色丝袜视频| 亚洲精品国产成人精品软件| 大肉大捧一进一出好爽视色大师| 亚洲综合色区在线观看| 五月婷婷之综合缴情| 2019一級特黃色毛片免費看| 丰满五十六十老熟女hd| 四虎永久在线精品免费视频观看| 国产+成+人+亚洲欧洲自线| 国产伦精品一区二区三区妓女| 国产成人精品三上悠亚| 中文人妻熟妇乱又伦精品| 欧美成人精品一区二区三区色欲| 国产精品亚洲αv天堂无码| 免费无码午夜福利片| 成人免费无码大片a毛片户外| 午夜大片免费男女爽爽影院| 伊人色综合久久天天小片| 亚洲国产成人精品无码区花野真一 | 韩国19禁主播深夜福利视频| 亚洲人成网亚洲欧洲无码|