在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Semaphorin-6A (Sema6a), partial

Recombinant Mouse Semaphorin-6A (Sema6a), partial

  • 中文名稱(chēng)：
    小鼠Sema6a重組蛋白
  • 貨號(hào)：
    CSB-YP020996MO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    小鼠Sema6a重組蛋白
  • 貨號(hào)：
    CSB-EP020996MO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    小鼠Sema6a重組蛋白
  • 貨號(hào)：
    CSB-EP020996MO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    小鼠Sema6a重組蛋白
  • 貨號(hào)：
    CSB-BP020996MO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    小鼠Sema6a重組蛋白
  • 貨號(hào)：
    CSB-MP020996MO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sema6a
  • Uniprot No.：
  • 別名：
    Sema6a; Semaq; Semaphorin-6A; Semaphorin Q; Sema Q; Semaphorin VIA; Sema VIA; Semaphorin-6A-1; SEMA6A-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
  • 基因功能參考文獻(xiàn)：
    1. These findings implicate Semaphorin-6A - Plexin-A2/Plexin-A4 interactions in dorsal lateral geniculate nucleus axon guidance and in the spatiotemporal organization of guidepost cell populations in the mammalian subpallium. PMID: 28438183
    2. Shear stress-regulated miR-27b promotes the interaction of endothelial cells with pericytes, partly by repressing SEMA6A and SEMA6D. PMID: 28453731
    3. mutations in Sema6A, and/or possibly interacting genes, may result in dysfunction at the level of neuronal networks with associated behavioural phenotypes of relevance to neuropsychiatric disorders PMID: 28109776
    4. The experiments reveal the complex nature of Sema6A biochemical functions and the molecular logic of the context-dependent interactions between Sema6A and PlxnA2. PMID: 27392094
    5. Using time-lapse videomicroscopy we provide evidence that Sema6A/PlexinA2 signaling participates to interkinetic nuclear migration of retinal progenitor cell PMID: 27301906
    6. findings reveal a unique function of Nrf2 in reprogramming ischemic tissue toward neurovascular repair via Sema6A regulation, providing a potential therapeutic strategy for ischemic retinal and CNS diseases PMID: 26621751
    7. Tangential migration is selectively altered in cerebellar neurons of Sema6A knockouts. PMID: 25284064
    8. semaphorin 6A is expressed in On starburst amacrine cell. PMID: 24179230
    9. Sema6A expressed in oligodendrocyte precursor cells is involved in their autonomous migration through ligand-receptor interaction with Plexin-A4 expressed in surrounding cells. PMID: 23376059
    10. The results of this study suggested that Sema6A might have a role in myelination by controlling oligodendrocyte differentiation. PMID: 22777942
    11. Adult Sema6A-null mice exhibit reduced tumor, matrigel, and choroidal angiogenesis compared with controls. Here we show that it also regulates vascular development and adult angiogenesis. PMID: 23007403
    12. null mutations in Sema6A or PlexinA4 (PlexA4) exhibit a pronounced defect in OPL stratification of horizontal cell axons without any apparent deficits in bipolar cell dendrite or photoreceptor axon targeting. PMID: 22593055
    13. Mice with mutations in Sema6A or the interacting genes may thus represent a highly informative model for how neurodevelopmental defects can lead to anatomical dysconnectivity. PMID: 22132072
    14. the transmembrane semaphorin Sema6A signals through its receptor PlexinA4 (PlexA4) to control lamina-specific neuronal stratification in the mouse retina PMID: 21270798
    15. crystal structures of cognate complexes of the semaphorin-binding regions of plexins B1 and A2 with semaphorin ectodomains (human PLXNB1(1-2)-SEMA4D(ecto) and murine PlxnA2(1-4)-Sema6A(ecto)), plus unliganded structures of PlxnA2(1-4) and Sema6A(ecto) PMID: 20877282
    16. regulates lamina-restricted projection of hippocampal mossy fiber.(review) PMID: 21089322
    17. crystal structures of the semaphorin 6A (Sema6A) receptor-binding fragment and the plexin A2 (PlxnA2) ligand-binding fragment in both their pre-signalling (that is, before binding) and signalling (after complex formation) states PMID: 20881961
    18. suggesting that a Sema6A-Plexin-A4 cis interaction serves as an inhibitory mechanism. PMID: 20606624
    19. During cerebellum development, Sema6A is selectively expressed by postmitotic granule cells during their tangential migration in the deep external granule cell layer, but not during their radial migration. PMID: 16205717
    20. Centrosome-nucleus coupling and coordinated motility were strongly perturbed in Sema6a-deficient granule cells suggesting that semaphorin-plexin signaling modulates cell migration by controlling centrosome positioning. PMID: 18327254
    21. Data show that Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. PMID: 19063725

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Semaphorin family
  • 組織特異性：
    Particularly high levels in spinal cord, cerebellum, metencephalon, superior and inferior colliculus, diencephalon, olfactory bulb and eye.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 国产亚洲日韩欧美另类第八页| 四虎国产精品永久地址49| 精品丝袜国产自在线拍小草| 国产精品国产三级国快看| 无尺码精品产品日韩| 少妇挑战黑人高潮惨叫| 国产按头口爆吞精在线视频| 国产精品日本亚洲欧美| 热99re久久精品| 推油少妇久久99久久99久久| 超碰国产精品人人做人人爱| 九九九精品成人免费视频| 久久综合av免费观看| 精品国产一区二区三区四区vr | 2020久久超碰国产精品最新| 精品国产一区二区三区四区| 久激情内射婷内射蜜桃| 亚洲高清有码中文字| 深夜国产成人福利在线观看| 波多野结衣一区二区三区av高清| 国产成人无码区免费内射一片色欲| 国产成人精品福利一区二区三区| 东京热大乱系列无码| 日韩欧美在线综合网另类| 中文字幕乱码人妻二区三区| 精品久久一区二区乱码| 国产免费二卡3卡四卡| 熟妇人妻一区二区三区四区| 国产精品成人网站| 国产精品夜夜春夜夜爽久久| 西西人体444www高清大胆| 国产精品亚洲专区无码不卡| 日韩在线视频线观看一区| 亚洲精品综合一区二区| 免费精品99久久国产综合精品| 亚洲中文字幕无码专区| 国产按头口爆吞精在线视频| 欧美精品videossex少妇| 131美女爱做视频| 少妇与子乱在线观看| 天天狠天天添日日拍|