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  4. Recombinant Mouse SH2 domain-containing protein 4A (Sh2d4a)

Recombinant Mouse SH2 domain-containing protein 4A (Sh2d4a)

  • 中文名稱：
    小鼠Sh2d4a重組蛋白
  • 貨號：
    CSB-YP875230MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sh2d4a重組蛋白
  • 貨號：
    CSB-EP875230MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sh2d4a重組蛋白
  • 貨號：
    CSB-EP875230MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sh2d4a重組蛋白
  • 貨號：
    CSB-BP875230MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sh2d4a重組蛋白
  • 貨號：
    CSB-MP875230MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sh2d4a
  • Uniprot No.：
  • 別名：
    Sh2d4a; SH2 domain-containing protein 4A
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-421
  • 氨基酸序列
    MLRQILSDMF IDPDLLAELS EEQKQILFYK MREEQIRRWK EREAAMERKE SLPVKSRPKK ENGKSVHWKL GADKQVWVWV MGEHHLDKPY DVLCDEILAE REHLRAAKDS ELRKTQSLEL ANSLKIKSQN CDLQAMKKTE PQNVTRKAAS EEASGQGPRA IPTRKDDKAQ TKPVKEKDHE EMKQTEDEKT KQIYKSWKED SEWQASLRKS KAADEKRRSL AKQAREDYKR LSQRGRSGDG LQNPLTGPQK PRRPPLPPKP QFLQPLGIPP KSLGNQGVIR TEISSAQMDT IRWFKEEQLP FRAGYQKNSD TIAPWFHGIL TLKKANELLS TGVPGSFLIR VSEKIKGYAL SYLSEEGCKH FLIDASANSY SFLGVDQLQH ATLADLVEYH KEEPITSLGK ELLLYPCGQQ DKLPDYLELF Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
  • 基因功能參考文獻：
    1. SH2D4A is dispensable for TCR signal transduction in T cells PMID: 18641339
  • 亞細胞定位：
    Cytoplasm. Note=Located at podocyte foot processes.
  • 組織特異性：
    In the kidney, expressed only in the glomerulus. Expressed in T-cells, B-cells, macrophages and dendritic cells (at protein level). In adult, highest levels are found in muscle and lung with lower levels in kidney.
  • 數據庫鏈接：


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