在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Rho-related GTP-binding protein RhoE (Rnd3)

Recombinant Mouse Rho-related GTP-binding protein RhoE (Rnd3)

  • 中文名稱：
    小鼠Rnd3重組蛋白
  • 貨號：
    CSB-YP019813MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Rnd3重組蛋白
  • 貨號：
    CSB-EP019813MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Rnd3重組蛋白
  • 貨號：
    CSB-EP019813MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Rnd3重組蛋白
  • 貨號：
    CSB-BP019813MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Rnd3重組蛋白
  • 貨號：
    CSB-MP019813MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Rnd3
  • Uniprot No.：
  • 別名：
    Rnd3; Arhe; Rhoe; Rho-related GTP-binding protein RhoE; Rho family GTPase 3; Rnd3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-241
  • 氨基酸序列
    MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS C
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
  • 基因功能參考文獻：
    1. Rnd3 acted as a novel proangiogenic factor involved in cardiac responsive angiogenesis through HIF1alpha-VEGFA signaling promotion. PMID: 26781283
    2. These results indicate that RhoE plays a role in suppressing tumor initiation and progression. PMID: 26036260
    3. Rnd3 is a novel factor involved in intracellular calcium homeostasis regulation in the heart. PMID: 25348166
    4. Animals with Rnd3 haploinsufficiency are predisposed to hemodynamic stress. Hyperactivation of Rho kinase activity is responsible in part for the apoptotic cardiomyopathy development. PMID: 24901055
    5. Data show that the Plexin B2 receptor interacts physically and functionally with Rnd3 and stimulates RhoA activity in migrating cortical neurons. PMID: 24572910
    6. RhoE is indispensable for osteoclast migration and bone resorption by maintaining fast actin turnover in podosomes. RhoE activates podosome component cofilin by inhibiting its Rock-mediated phosphorylation. PMID: 24284899
    7. although Rnd3 expression is controlled transcriptionally by Ascl1, this proneural factor is itself required in radial glial progenitors only for proper orientation of cell divisions PMID: 23535656
    8. Rnd3 is a regulator of Notch1 signaling PMID: 23630292
    9. These findings support our previous report revealing the important role of RhoE in the normal development of the nervous system PMID: 22428561
    10. the important role of Rnd3/RhoE in the normal development PMID: 21552537
    11. a well defined Rnd3 effector Syx PMID: 20811643
    12. RhoE induces stress fiber disassembly by directly binding ROCK I and inhibiting it from phosphorylating downstream targets PMID: 12773565
    13. RhoE inhibits cell cycle progression upstream of the pRb checkpoint. PMID: 15340047
    14. study shows RhoE physiological upregulation before myoblast fusion is responsible for the decrease in RhoA and ROCKI activities, which are required for the fusion process; therefore, we conclude that RhoE is an essential regulator of myoblast fusion PMID: 18369372
    15. Our results suggest that RhoE can play important roles in the postnatal development and maturation of the CNS, especially in the migratory processes affecting the neurones. PMID: 19589369
    16. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation. PMID: 19850923

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus membrane; Peripheral membrane protein.
  • 蛋白家族：
    Small GTPase superfamily, Rho family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产精品无码人妻一区二区在线| 国产成人无码www免费视频播放 | 国产萌白酱喷水视频在线观看 | 欧美日韩视频无码一区二区三| 久久精品国产精品亚洲| 色翁荡息又大又硬又粗又爽电影| 中文字字幕在线中文乱码| 在线岛国片免费无码av| 久热这里只精品99国产6-99re视…| 亚洲中文字幕不卡无码| 国产成人无码激情视频| 国产精品天天狠天天看| 成人性做爰aaa片免费看不忠| 国产又粗又硬又大爽黄老大爷视| 国产亚洲精品aaaaaaa片| 国产精品高潮呻吟av久久小说| 亚洲 制服丝袜 中文字幕 在线| 8x国产精品视频| 国产农村老太xxxxhdxx| 国产免费又爽又色又粗视频| 色悠久久久久综合网香蕉| 男女啪啪免费观看的网址| 亚洲人成无码网站在线观看| 女人被狂躁的高潮免费视频| 国产免费视频| 久久婷婷综合激情亚洲狠狠| 国产做爰xxxⅹ久久久小说| 久久午夜无码鲁丝片直播午夜精品 | 性无码专区无码| 国内精品免费久久久久电影院| 中文字幕久久综合伊人| 久久精品成人免费观看| 精品国产在天天在线观看| 久久久久高潮综合影院| 97国产精东麻豆人妻电影| 国产成人无码av片在线观看不卡| 国产精品va在线观看老妇女| 欧美群交射精内射颜射潮喷| 欧美人与动人物牲交免费观看久久| 99j久久精品久久久久久| 亚洲v国产v天堂a无码二区|