在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Rho guanine nucleotide exchange factor 7 (Arhgef7), partial

Recombinant Mouse Rho guanine nucleotide exchange factor 7 (Arhgef7), partial

  • 中文名稱：
    Recombinant Mouse Rho guanine nucleotide exchange factor 7(Arhgef7) ,partial
  • 貨號：
    CSB-YP884149MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho guanine nucleotide exchange factor 7(Arhgef7) ,partial
  • 貨號：
    CSB-EP884149MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho guanine nucleotide exchange factor 7(Arhgef7) ,partial
  • 貨號：
    CSB-EP884149MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho guanine nucleotide exchange factor 7(Arhgef7) ,partial
  • 貨號：
    CSB-BP884149MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho guanine nucleotide exchange factor 7(Arhgef7) ,partial
  • 貨號：
    CSB-MP884149MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Arhgef7; Kiaa0142; Pak3bp; Rho guanine nucleotide exchange factor 7; Beta-Pix; PAK-interacting exchange factor beta; p85SPR
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
  • 基因功能參考文獻：
    1. Phosphorylation of LRRK2 by casein kinase 1alpha regulates trans-Golgi clustering via differential interaction with ARHGEF7. PMID: 25500533
    2. It provides for the first time, to our knowledge, a possible mechanism for the concerted action of tyrosine kinases, GIT1/betaPIX proteins, and Ca(2+) in the propagation of signals leading to the regulation of microtubule nucleation in activated mast cells. PMID: 25821222
    3. beta-Pix controls the spatial localization of Rac1 activity to drive collective AVE migration at a critical stage in mouse development. PMID: 25512563
    4. Therefore, we propose that PKCgamma positively modulates dopamine release through beta2PIX phosphorylation. PMID: 25009260
    5. Glucose stimulates Cav-1 and induces its dissociation from Cdc42, to promote Cdc42-betaPix binding and Cdc42 activation, and to trigger downstream signaling and ultimately sustain insulin release. PMID: 21828338
    6. a model by which SNX27 regulates trafficking of beta-Pix to focal adhesions and thereby influences cell motility. PMID: 21926430
    7. betaPix-b(L) induced pinocytosis through cooperative action of the CH and Dbl homology (DH) domains, demonstrating the role of betaPix-b(L) in the regulation of membrane dynamics PMID: 21249427
    8. Stat3 binds to betaPIX, a Rac1 activator,and regulates Rac1 activity to modulate the organization of actin cytoskeleton and directional migration PMID: 19861492
    9. P85 beta-PIX, located downstream of Rac1, is a key regulator for the activations of FAK or p38 MAP kinase and plays a pivotal role in focal complex formation and cell motility. PMID: 15893751
    10. the regulated phosphorylation of Cool-1 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation. PMID: 16892055
    11. These results show that the interaction between Abi-1 and betaPIX is involved in the formation of growth factor-induced membrane dorsal ruffles. PMID: 16940963
    12. Results suggest that the PAK-PIX-GIT1 complex is critical for Erk-dependent myosin phosphorylation and vascular permeability. PMID: 17429073
    13. The association of PLCgamma1 with complexes containing GIT1 and beta-Pix is essential for its role in integrin-mediated cell spreading and motility. As a component of this complex, PLCgamma1 is also involved in the activation of Cdc42 and Rac1. PMID: 17562871

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, focal adhesion. Cell projection, ruffle. Cytoplasm, cell cortex. Cell projection, lamellipodium. Note=Detected at cell adhesions. A small proportion is detected at focal adhesions.
  • 組織特異性：
    Seems to be expressed in the central nervous system. Isoform B, isoform C and isoform E are expressed with highest levels in brain and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 18禁成年免费无码国产| 大香伊蕉在人线国产最新75| 蕾丝av无码专区在线观看| 国产av亚洲aⅴ一区二区| 99久久99视频只有精品| 九九re6热在线视频精品66| 国产精品网站在线观看免费传媒| 久久久婷婷五月亚洲97号色| 99精品视频在线观看婷婷| 久久人妻xunleige无码| 少妇精品视频无码专区| 免费人成激情视频在线观看冫| 女人喷液抽搐高潮视频| 欧美精品亚洲精品日韩专区va| 国产精品免费观看调教网| 国产人成无码视频在线1000| 国产精品污www一区二区三区| 中文字幕aⅴ人妻一区二区| 新版资源天堂中文| 成年动漫18禁无码3d动漫| 又大又紧又粉嫩18p少妇| 亚洲一卡二卡三卡四卡| 亚洲国产天堂久久综合| 欧美99久久无码一区人妻a片| 亚洲精品无码永久中文字幕| 欧美丰满老妇性猛交| 欧美色综合天天久久综合精品 | 午夜视频在线观看免费完整版| 日韩一区二区三区无码人妻视频| 色77久久综合网| 国产成a人亚洲精v品无码 | 亚洲欧洲专线一区| 亚洲精品久久yy5099| 国产高清在线精品一区二区三区 | 亚洲综合在线另类色区奇米| 亚 洲 成 人 网站在线观看| 欧美天天拍在线视频| 青春草在线视频观看| 婷婷开心激情综合五月天 | 亚洲综合激情七月婷婷| 人妻无码一区二区三区|