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  4. Recombinant Mouse Rho GTPase-activating protein 24 (Arhgap24)

Recombinant Mouse Rho GTPase-activating protein 24 (Arhgap24)

  • 中文名稱：
    Recombinant Mouse Rho GTPase-activating protein 24(Arhgap24)
  • 貨號：
    CSB-YP805397MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho GTPase-activating protein 24(Arhgap24)
  • 貨號：
    CSB-EP805397MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho GTPase-activating protein 24(Arhgap24)
  • 貨號：
    CSB-EP805397MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho GTPase-activating protein 24(Arhgap24)
  • 貨號：
    CSB-BP805397MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Rho GTPase-activating protein 24(Arhgap24)
  • 貨號：
    CSB-MP805397MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Arhgap24
  • Uniprot No.：
  • 別名：
    Arhgap24; Rho GTPase-activating protein 24; Rho-type GTPase-activating protein 24
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-747
  • 氨基酸序列
    MEERCESTES PQGQGRKNTK CGWLRKQGGF VKTWHTRWFV LKGDQLYYFK DEDETKPLGT IFLHGNKVIE HPCNEENPGK FLFDVVPGGE RDRMTANHES YLLMASTQND MEDWVKSIRR VIWGPFGGGI FGQKLEDTVR YEKRYGNRLA PMLVEQCVDF IRQRGLKEEG LFRLPGQANL VKELQDAFDC GEKPSFDSNT DVHTVASLLK LYLRELPEPV VPYAKYEDFL SCATLLSKEE EAGVKELMKQ VKSLPVVNYN LLKYICRFLD EVQSYSGVNK MSAQNLATVF GPNILRPKVE DPLTIMEGTV VVQQLMSVMI SKHDRLFPKD TEPQSKPQDG PNSNNNDGHK KATMGQLQNK ENNNTKESPV RRCSWDKPES PQRSSVDNGS PTALSGSKTN SPRNSIHKLD ISRSPPLMVK KNPAFNKGSG IVTNGSFSSS NAEGVEKPQT TPNGSLQARR TSSLKSSGTK MGTHSVQNGT VRMGILNTDT LGNSLNGRSM SWLPNGYVTL RDNKQKEPAG ESGQHNRLST YDNVHQQFSS MSLDDKHSVD SATWSTSSCE ISLPENSNSC RSSTTTCPEQ DFYVGNFEDP VLDGPPQDDL SHPGDYENKS DRRSVGGRSS RATSSSDNSE TFVGNTSSNH SALHSLVSSL KQEMTKQKIE YESRIKSLEQ RNLTLETEML SLHDELDQER KKFTMIEIKM RNAERAKEDA EKRNDMLQKE MEQFFSTFGD LTVEPRRSER GNTIWIQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
  • 基因功能參考文獻：
    1. Increased levels of active Rac1 and Cdc42 were measured in Arhgap24 knockdown experiments, which influenced podocyte cell shape and membrane dynamics. PMID: 21911940
  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection.
  • 數據庫鏈接：


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