在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Receptor activity-modifying protein 2 (Ramp2), partial

  • 中文名稱:
    小鼠Ramp2重組蛋白
  • 貨號:
    CSB-YP892990MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Ramp2重組蛋白
  • 貨號:
    CSB-EP892990MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Ramp2重組蛋白
  • 貨號:
    CSB-EP892990MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Ramp2重組蛋白
  • 貨號:
    CSB-BP892990MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Ramp2重組蛋白
  • 貨號:
    CSB-MP892990MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ramp2; Receptor activity-modifying protein 2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.
  • 基因功能參考文獻(xiàn):
    1. The AM-RAMP2 system exerts crucial vasoprotective effects after vascular injury and could be a therapeutic target for the treatment of vascular diseases. PMID: 28324104
    2. Results provide in vivo evidence of a role for RAMP2 in placental development distinct from the RAMP2-calcitonin receptor-like receptor/adrenomedullin signaling paradigm; decreases Pthr1 expression and causes a blunted response to systemic parathyroid hormone; and identify additional pathways underlying the endocrine and fertility defects of the previously characterized Ramp2 heterozygous adult females. PMID: 28727763
    3. the Adrenomedullin-RAMP2 system regulates vascular integrity, whereas RAMP2 deletion promotes vascular permeability PMID: 27307317
    4. RAMP2 is essential for early vascular development and knockout-mice die in utero. PMID: 25264174
    5. These results indicate the AM-RAMP2 system works to protect nerve cells from both acute and chronic cerebral ischemia by maintaining cerebral blood flow suppressing oxidative stress, and in the case of chronic ischemia, enhancing capillary growth. PMID: 25252154
    6. It is not only an angiogenesis factor, but maintains hemostasis of blood vessels and organs. PMID: 24813793
    7. The AM-RAMP2 system is a key determinant of vascular integrity and homeostasis from prenatal stages through adulthood. PMID: 23355623
    8. These data demonstrate that the adrenomedullin-RAMP2 system is essential for cardiac metabolism and homeostasis. PMID: 23297372
    9. Adrenomedullin-RAMP2 system is the potential target for the induction of liver sinusoidal endothelial cells. PMID: 21782867
    10. this work reveals an essential role for RAMP2 in endocrine physiology and provides the first in vivo evidence for a physiological role of RAMP2 beyond that of AM/CLR signaling PMID: 21566080
    11. expressed in osteoclast-like cells PMID: 15691893
    12. RAMP2 plays a key role in the sensitivity and potency of AM-induced hypotensive responses via the AM1 receptor. PMID: 16373602
    13. RAMP2 and RAMP3 have distinct physiological functions throughout embryogenesis, adulthood, and old age PMID: 17470425
    14. RAMP2 is a key determinant of the effects of AM on the vasculature and is essential for angiogenesis and vascular integrity. PMID: 18097473
    15. the vascular smooth muscle AM1 receptor RAMP2 acts at a local level to protect against hypertension-induced vascular hypertrophy and inflammation PMID: 19858409

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    RAMP family
  • 組織特異性:
    Ubiquitous. Expressed predominantly in embryonic brain, lung and gut and in adult heart, lung, skeletal muscle and brain.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 天天噜日日噜狠狠噜免费| 国产放荡对白视频在线观看| 日韩人妻无码中文字幕视频| 日本真人做爰免费视频120秒| 朝鲜女人大白屁股ass| 亚洲精品国产精品制服丝袜 | 少妇性bbb搡bbb爽爽爽欧美| 99精品国产在热久久婷婷| 中文乱码人妻系列一区| 亚洲精品av一二三区无码| 把腿张开老子臊烂你多p视频 | 无码人妻精品一区二区蜜桃色欲 | 少妇精品无码一区二区三区| 久久综合久久88中字幕文| 亚洲一区二区三区无码av| 无码精品黑人一区二区三区| 日日碰狠狠躁久久躁综合小说| 久久精品中文闷骚内射| 国产模特嫩模私拍视频在线| 大香网伊人久久综合网2018| 国产精品无码午夜福利| 4438xx亚洲最大五色丁香| 好了av四色综合无码久久| 青青草国产精品人人爱| 真人与拘做受免费视频一| 午夜精品一区二区三区免费视频| 玩弄人妻少妇500系列网址| 国产精品久久久久9999不卡| 国产又黄又大又粗视频| 久久婷婷色综合一区二区| 中文乱码人妻系列一区| 国产公开久久人人97超碰| 精品人无码一区二区三区| 先锋影音最新色资源站| 一本一本久久a久久综合精品蜜桃| 欧美日韩国产中文高清视频| 中文无码精品一区二区三区| 天堂资源在线www中文| 青青草国产精品欧美成人| 97久久精品人人槡人妻人| 黄a无码片内射无码视频|