在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Ras-specific guanine nucleotide-releasing factor 2 (Rasgrf2), partial

Recombinant Mouse Ras-specific guanine nucleotide-releasing factor 2 (Rasgrf2), partial

  • 中文名稱：
    小鼠Rasgrf2重組蛋白
  • 貨號：
    CSB-YP019361MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Rasgrf2重組蛋白
  • 貨號：
    CSB-EP019361MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Rasgrf2重組蛋白
  • 貨號：
    CSB-EP019361MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Rasgrf2重組蛋白
  • 貨號：
    CSB-BP019361MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Rasgrf2重組蛋白
  • 貨號：
    CSB-MP019361MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Rasgrf2; Grf2; Ras-specific guanine nucleotide-releasing factor 2; Ras-GRF2; Ras guanine nucleotide exchange factor 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
  • 基因功能參考文獻：
    1. Nuclear migration in retinal cone photoreceptors is altered in GRF2 knockout mice. PMID: 26743081
    2. adaptations in the noradrenergic system contribute to the Rasgrf2 enhanced risk of alcoholism. PMID: 24737505
    3. Findings indicate that GRF2 regulates both the basal level and environmentally induced increase of newborn neuron survival, as well as in the induction of a distinct form of synaptic plasticity of newborn neurons that contributes to learning and memory PMID: 24894950
    4. These data suggest that Rasgrf2 controls dopaminergic signalling and adaptations to alcohol also in other brain regions, beyond the nucleus accumbens. PMID: 25454123
    5. these results suggest that betaarrestin1 regulates rasgrf2 gene expression and Rac activation to affect membrane protrusion and cell migration and invasion. PMID: 24692549
    6. RASGRF2 has a role in the regulation of mesolimbic dopamine neuron activity, reward response, and alcohol use and abuse PMID: 23223532
    7. Study demonstrates that NR2A-, but not NR2B, containing NMDA receptors induce LTP in pyramidal neurons of the CA1 hippocampus from 1 month old mice through Ras-GRF2 and Erk. PMID: 20661302
    8. These data reveal unexpected negative roles for Vav1 and RasGRF2 in different stages of T-cell lymphoma progression. PMID: 20011522
    9. Mediates forms of synaptic plasticity by coupling different classes of NMDA receptors to distinct MAP kinase pathways PMID: 16467520
    10. These results identify RasGRF2 as an additional component of the signaling machinery involved in T-cell receptor- and NF-AT-mediated immune responses. PMID: 17923690

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 組織特異性：
    Expressed in brain in the nucleus of the solitary tract. Not observed in the hippocampus (at protein level).
  • 數據庫鏈接：

    KEGG: mmu:19418

    UniGene: Mm.248630



主站蜘蛛池模板： av无码久久久精品免费| 国产极品美女到高潮| 精品玖玖玖视频在线观看| 无码av不卡免费播放| 精品日产一卡2卡三卡4卡在线| 中文字幕一区二区三区精彩视频| 国产精品亚洲一区二区三区| 亚洲欧美日韩在线资源观看| 午夜三级a三级三点在线观看| 国产精品18久久久久久vr| 成人性生交大片免费看小说| 97精品国产久热在线观看| 无码精品国产d在线观看 | 国产成人综合久久免费| 国产人妖视频一区二区| 人人妻人人澡人人爽欧美一区九九| 欧美高潮喷水大叫| 国产 | 欧洲野花视频天堂视频p | 国产人妻人伦精品久久久| 久久99精品久久久大学生| 中文字幕av高清片| 四库影院永久国产精品地址| 亚洲成av人片一区二区三区 | 精品国产va久久久久久久冰| 天天弄天天模| 久久精品99av高久久精品| 顶级欧美熟妇高潮xxxxx| 亚欧免费无码aⅴ在线观看| 99久久久无码国产精品秋霞网 | 午夜免费啪视频观看视频| 2022国产成人精品视频人| 天天燥日日燥| 开心色婷婷色五月激情| 国产美女裸体无遮挡免费视频| 成人内射国产免费观看| 欧洲亚洲国产成人综合色婷婷| 一卡二卡3卡四卡网站精品| 日韩欧美高清dvd碟片| 大肉大捧一进一出视频出来呀 | 无码乱肉视频免费大全合集| 国产成人无码性教育视频|