在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Pulmonary surfactant-associated protein B (Sftpb)

Recombinant Mouse Pulmonary surfactant-associated protein B (Sftpb)

  • 中文名稱：
    小鼠Sftpb重組蛋白
  • 貨號：
    CSB-YP021173MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sftpb重組蛋白
  • 貨號：
    CSB-EP021173MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sftpb重組蛋白
  • 貨號：
    CSB-EP021173MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sftpb重組蛋白
  • 貨號：
    CSB-BP021173MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sftpb重組蛋白
  • 貨號：
    CSB-MP021173MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sftpb
  • Uniprot No.：
  • 別名：
    Sftpb; Sftp3; Pulmonary surfactant-associated protein B; SP-B; Pulmonary surfactant-associated proteolipid SPL(Phe)
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    192-270
  • 氨基酸序列
    LPIPLPFCW LCRTLIKRVQ AVIPKGVLAV AVSQVCHVVP LVVGGICQCL AERYTVLLLD ALLGRVVPQL VCGLVLRCST
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
  • 基因功能參考文獻：
    1. Surfactant protein B suppresses lung cancer progression by inhibiting secretory phospholipase A2 activity and arachidonic acid production. PMID: 28743125
    2. These data provided a plausible mechanism linking maternal vitamin D deficiency with altered postnatal lung function. PMID: 27121020
    3. Surfactant protein B had decreased levels in influenza A virus PR8-infected cells, which was confirmed by immunoblotting and immunofluorescence assays. PMID: 25965799
    4. macrophages participate in the repression of SFTPB expression by LPS, and that macrophage-released cytokines (including TNF) regulate the transcription factor CEBPB PMID: 23590297
    5. ErbB4 regulates the expression of surfactant protein B in fetal lung maturation, helping to prepare for the fetal-neonatal transition. PMID: 21317380
    6. The stimulatory effects of estrogen on Sftpb are under transcriptional control of ErbB4. PMID: 21777626
    7. SP-B contributes to innate host defense of the lung by supplementing the nonoxidant antimicrobial defenses of alveolar macrophages PMID: 20007532
    8. DNA methylation and chromatin modifications cooperate with Nkx2-1 to regulate Sftpb gene cell specific expression. PMID: 19906647
    9. formation of the intersubunit disulfide bridge is not critical for SP-B function PMID: 12133857
    10. The late asthmatic response is linked with increased surface tension and reduced surfactant protein B in mice. PMID: 12225952
    11. This protein inhibits endotoxin-induced lung inflammation. PMID: 12594064
    12. Reduction of alveolar SP-B content causes surfactant dysfunction and respiratory failure, indicating that SP-B is required for postnatal lung function. PMID: 12639841
    13. SP-B expression is regulated by PPARgamma in the lung PMID: 12829715
    14. napsin, cathepsin H, and at least one other enzyme are involved in maturation of the biologically active SP-B peptide PMID: 14766755
    15. Results indicate that hypoxia-induced mitogenic factor induces surfactant protein B and C production in mouse lungs and cell lines via activation of phosphatidylinositol 3-kinase/Akt and ERK1/2 mitogen-activated protein kinases. PMID: 16166744
    16. absence of HO-1 in the lung parenchyma, not in bone marrow-derived inflammatory cells, was responsible for enhanced SP-B downregulation and severe physiologic lung dysfunction PMID: 16309574
    17. Via promoter mutation analysis, adjacent TTF-1 binding sites within the proximal promoter region of SP-C were found to be essential for TTF-1/TAP26-enhanced SP-C promoter activity. PMID: 16630564
    18. SP-B controls surface tension by forming a surfactant phospholipid film that regulates shape and nonspecific phagocytic activity of alveolar macrophages on the alveolar surface. PMID: 16632521
    19. ABCA3 is necessary for lamellar body biogenesis, surfactant protein-B processing, and lung development late in gestation. PMID: 17540762
    20. Three novel Sp1 binding motifs were identified in the mouse SP-B promoter. PMID: 19096034
    21. Results support the idea that maintenance of surfactant-associated protein B expression is critical to survival during acute lung injury. PMID: 19131640
    22. The surface tension-lowering properties of Sftpb play an important role in the regulation of pulmonary vascular perfusion. PMID: 19202005
    23. Maintaining Sftpb is critical to survival during acute lung injury PMID: 19131640

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space, surface film.
  • 數據庫鏈接：


主站蜘蛛池模板： 狠狠躁夜夜躁人人爽天天5| 一中文字幕日产乱码va| 欧洲无码一区二区三区在线观看| 鲁丝一区二区三区免费| 国产精品一区二区av麻豆| 免费能直接看黄的视频| 国产亚洲综合久久系列| 亚洲中文字幕无码爆乳av| 最近免费中文字幕大全免费版视频| 男插女高潮一区二区| 日韩视频 中文字幕 视频一区| 久久综合亚洲色一区二区三区| 肉大榛一进一出免费视频| 天天摸天天做天天爽天天弄| 色婷婷亚洲一区二区综合| 亚洲国产精品久久精品| 一群黑人大战亚裔女在线播放 | 狠狠噜天天噜日日噜色综合| 都市激综合小说区另类区| 国产女人被狂躁到高潮小说| 亚洲人成无码网www电影麻豆| 亚洲国产精品成人影片久久| 性做久久久久久久免费看| 日韩超碰人人爽人人做人人添| 亚洲a成人无码网站在线| 亚洲a∨精品一区二区三区| 一本大道熟女人妻中文字幕在线| 熟女少妇在线视频播放| 亚洲中文字幕无码一去台湾| 美女网站免费福利视频| 久久久久无码精品亚洲日韩| 午夜亚洲乱码伦小说区69堂| 亚洲色成人影院在线观看| 美女无遮挡免费视频网站| 香港日本三级亚洲三级| 尹人香蕉99久久综合网站| 亚洲熟妇av一区二区三区漫画| 丝袜老师办公室里做好紧好爽 | 色噜噜狠狼综合在线| 香草乱码一二三四区别| 狂野欧美性猛交xxxx|