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  4. Recombinant Mouse Protein arginine N-methyltransferase 2 (Prmt2)

Recombinant Mouse Protein arginine N-methyltransferase 2 (Prmt2)

  • 中文名稱：
    小鼠Prmt2重組蛋白
  • 貨號：
    CSB-YP886429MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Prmt2重組蛋白
  • 貨號：
    CSB-EP886429MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Prmt2重組蛋白
  • 貨號：
    CSB-EP886429MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Prmt2重組蛋白
  • 貨號：
    CSB-BP886429MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Prmt2重組蛋白
  • 貨號：
    CSB-MP886429MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Prmt2
  • Uniprot No.：
  • 別名：
    Prmt2; Hrmt1l1Protein arginine N-methyltransferase 2; EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-448
  • 氨基酸序列
    MEAPGEGPCS ESQVIPVLEE DPVDYGCEMQ LLQDGAQLQL QLQPEEFVAI ADYTATDETQ LSFLRGEKIL ILRQTTADWW WGERAGCCGY IPANHLGKQL EEYDPEDTWQ DEEYFDSYGT LKLHLEMLAD QPRTTKYHSV ILQNKESLKD KVILDVGCGT GIISLFCAHH ARPKAVYAVE ASDMAQHTSQ LVLQNGFADT ITVFQQKVED VVLPEKVDVL VSEWMGTCLL FEFMIESILY ARDTWLKGDG IIWPTTAALH LVPCSAEKDY HSKVLFWDNA YEFNLSALKS LAIKEFFSRP KSNHILKPED CLSEPCTILQ LDMRTVQVPD LETMRGELRF DIQKAGTLHG FTAWFSVYFQ SLEEGQPQQV VSTGPLHPTT HWKQTLFMMD DPVPVHTGDV VHGFCCVTKK SGMEKAHVCL SELGCHVRTR SHVSTELETG SFRSGGDS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. May inhibit NF-kappa-B transcription, and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). Has a negative regulation effect on G1 to S transition of mitotic cell cycle. Involved in growth regulation. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 組織特異性：
    Expressed in liver, pancreas, lung, brain, skeletal muscle, heart, muscle and fat.
  • 數據庫鏈接：


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