在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Protein IMPACT (Impact)

Recombinant Mouse Protein IMPACT (Impact)

  • 中文名稱：
    小鼠Impact重組蛋白
  • 貨號：
    CSB-YP011696MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Impact重組蛋白
  • 貨號：
    CSB-EP011696MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Impact重組蛋白
  • 貨號：
    CSB-EP011696MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Impact重組蛋白
  • 貨號：
    CSB-BP011696MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Impact重組蛋白
  • 貨號：
    CSB-MP011696MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Impact
  • Uniprot No.：
  • 別名：
    Impact; Protein IMPACT; Imprinted and ancient gene protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-318
  • 氨基酸序列
    MAEEEVGNSQ RQSEEIEAMA AIYGEEWCVI DENAKIFCIR VTDFMDDPKW TLCLQVMLPS EYPGTAPPSY QLNAPWLKGQ ERADLSNSLE EIYVHNMGES ILYQWVEKIR DALIQKSQIT EPDPDVKKKT EEVEVESEED PILEHPPENP VKTLDLKISE ETQPETEELP PVAHGVPITD RRSTFQAHVA PVVCPEQVKL VLAKLYENKK IASATHNIYA YRIFCEDKQT FLQDCEDDGE TAAGGRLLHL MEILNVKNVM VVVSRWYGGI LLGPDRFKHI NNCARNILVE KNFTNTPDES TKNLGKKKVK KDKKKNDH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
  • 基因功能參考文獻：
    1. This study extends our understanding of the roles played by GCN1 in GCN2 activation induced by a variety of stress arrangements and suggests that IMPACT and YIH1 use similar mechanisms for regulating this eIF2alpha kinase. PMID: 24333428
    2. the participation of the GCN2-IMPACT module of translational regulation in a highly controlled step in the development of the nervous system. PMID: 23447528
    3. segmental duplication followed by enhancement of the promoter activity is responsible for the species-specific imprinting of Impact PMID: 15871461
    4. IMPACT ensures constant high levels of translation and low levels of CREB-2 and GADD53 in specific neuronal cells under amino acid starvation conditions. PMID: 15937339
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    IMPACT family
  • 組織特異性：
    Present in neurons in most areas of the brain. Present at high level in hypothalamus, particularly in the suprachiasmatic nucleus (at protein level). Preferentially expressed in brain, with a weaker expression in other tissues.
  • 數據庫鏈接：

    KEGG: mmu:16210

    STRING: 10090.ENSMUSP00000025290

    UniGene: Mm.8154



主站蜘蛛池模板： 无码国产精品成人| 国产成 人 综合 亚洲专区| 亚洲日韩va在线视频| 小13箩利洗澡无码视频网站| 又粗又大内射免费视频小说| 大肉大捧一进一出好爽app| 亚洲暴爽av人人爽日日碰| 野花社区免费观看在线www| 农民人伦一区二区三区| 久久久久成人精品无码| 国产aⅴ激情无码久久久无码| 中文字幕+乱码+中文乱码www| 96亚洲精华国产精华精华液| 欧美日韩在线亚洲综合国产人| 无码专区3d动漫精品免费| 一本精品99久久精品77| 中文在线www天堂网| 久久久久久久97| 欧美精品国产aⅴ一区二区在线| 成人亚洲欧美在线观看| 99久久国产成人免费网站| 人妻av中文字幕无码专区| 国产精品日本一区二区在线播放 | 99精品视频一区在线观看| 国产好大好硬好爽免费视频| 欧美老人巨大xxxx做受| 国产又爽又黄无码无遮挡在线观看| 成人无码在线视频网站| 国产好大好硬好爽免费视频| 国产伦精品免编号公布| 色偷偷av一区二区三区| 亚洲色偷偷偷网站色偷一区| 国产成人8x视频网站入口| 久久久久久自慰出白浆| 亚洲成av人在线视猫咪| 中文有码人妻字幕在线| 色视频www在线播放国产人成| 成人午夜精品无码区| 久久久久久伊人高潮影院| 中国白嫩丰满人妻videos| 日本一卡二卡不卡视频查询|