在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Potassium channel subfamily U member 1 (Kcnu1), partial

Recombinant Mouse Potassium channel subfamily U member 1 (Kcnu1), partial

  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-YP012100MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-EP012100MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-EP012100MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-BP012100MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-MP012100MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Kcnu1; Kcnma3; Ksper; Slo3; Potassium channel subfamily U member 1; Calcium-activated potassium channel subunit alpha-3; Calcium-activated potassium channel; subfamily M subunit alpha-3; Pore-forming subunit of the sperm-specific alkalization activated K(+) current; KSper; Slowpoke homolog 3; mSlo3; pH-sensitive maxi potassium channel
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
  • 基因功能參考文獻(xiàn)：
    1. Considering that capacitation-induced hyperpolarization is mediated by SLO3, we evaluated the action of cSrc inhibitors on the heterologously expressed SLO3 channel. PMID: 26060254
    2. These results establish a critical role of LRRC52 in KSPER channels and demonstrate that loss of a non-pore-forming auxiliary subunit results in severe fertility impairment. PMID: 25675513
    3. SLO3 K+ channels have a role in controlling calcium entry through CATSPER channels in sperm PMID: 25271166
    4. Using mice lacking both SLO3 and CATSPER1 subunits, the results show conclusively that the voltage-activated outward current present in Slo3 (-/-) sperm is abolished when CATSPER is also deleted. PMID: 23980198
    5. SLO3-dependent hyperpolarization PMID: 23577126
    6. KSper/Slo3 is the primary spermatozoan K(+) channel, and Slo3 is critical for fertility. PMID: 21427226
    7. Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition PMID: 20392696
    8. SLO3 is the principal potassium channel responsible for capacitation-induced hyperpolarization, and membrane hyperpolarization is crucial to the acrosome reaction. PMID: 20138882
    9. voltage and pH regulate a closed-open conformational change in a largely independent fashion PMID: 16940554
    10. increases in pH increase the fraction of more rapidly opening channels. PMID: 16940555
    11. native current observed in sperm is indeed carried by Slo3 channels. PMID: 19338774
    12. results argue that, for native mouse Slo3 channels, the beta4 subunit must be considered as a potential interaction partner and, furthermore, that KCNMB subunits may have functions unrelated to regulation of the Slo1 alpha subunit PMID: 19578543

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily
  • 組織特異性：
    Testis-specific. Mainly expressed in spermatocytes.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 极品少妇xxxx精品少妇偷拍| 色欲色香天天天综合网站| 99久久国产自偷自偷免费一区| 国产人成高清在线视频99最全资源| 97国产在线看片免费人成视频| 国产99视频精品免视看7| 女人高潮抽搐喷液30分钟视频| 亚洲人成影院在线观看| 俺也来俺也去俺也射| 少妇特殊按摩高潮惨叫无码| 国产成人综合在线女婷五月99播放| 免费va人成视频网站全| 国产成人无码短视频| 国产又滑又嫩又白| 亚洲日韩av无码中文字幕美国| 欧美 国产日韩 综合在线| 日日躁狠狠躁狠狠爱| 97无码免费人妻超级碰碰碰碰| 国产美女裸体无遮挡免费视频 | 日本乱妇乱子视频| 蜜臀av夜夜澡人人爽人人| 成a人片亚洲日本久久| 午夜性色福利在线视频福利 | 18禁白丝喷水视频www视频| 真人做作爱视频| 动漫精品无码h在线观看| 99久久精品费精品国产| 人人妻人人澡人人爽秒播| 西西人体www大胆高清| 国产白嫩漂亮美女在线观看| 国产成人av区一区二区三| 国产精品99久久久久久董美香| 女厕偷窥一区二区三区| 超碰色偷偷男人的天堂| 永久免费的av在线电影网| 人妻三级日本三级日本三级极| 日韩欧美在线综合网另类| 午夜精品一区二区三区的区别| 老熟妻内射精品一区| 国产成人亚洲综合无码品善网 | 久久婷婷久久一区二区三区|