在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Potassium channel subfamily U member 1 (Kcnu1), partial

Recombinant Mouse Potassium channel subfamily U member 1 (Kcnu1), partial

  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-YP012100MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-EP012100MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-EP012100MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-BP012100MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Kcnu1重組蛋白
  • 貨號(hào)：
    CSB-MP012100MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Kcnu1; Kcnma3; Ksper; Slo3; Potassium channel subfamily U member 1; Calcium-activated potassium channel subunit alpha-3; Calcium-activated potassium channel; subfamily M subunit alpha-3; Pore-forming subunit of the sperm-specific alkalization activated K(+) current; KSper; Slowpoke homolog 3; mSlo3; pH-sensitive maxi potassium channel
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
  • 基因功能參考文獻(xiàn)：
    1. Considering that capacitation-induced hyperpolarization is mediated by SLO3, we evaluated the action of cSrc inhibitors on the heterologously expressed SLO3 channel. PMID: 26060254
    2. These results establish a critical role of LRRC52 in KSPER channels and demonstrate that loss of a non-pore-forming auxiliary subunit results in severe fertility impairment. PMID: 25675513
    3. SLO3 K+ channels have a role in controlling calcium entry through CATSPER channels in sperm PMID: 25271166
    4. Using mice lacking both SLO3 and CATSPER1 subunits, the results show conclusively that the voltage-activated outward current present in Slo3 (-/-) sperm is abolished when CATSPER is also deleted. PMID: 23980198
    5. SLO3-dependent hyperpolarization PMID: 23577126
    6. KSper/Slo3 is the primary spermatozoan K(+) channel, and Slo3 is critical for fertility. PMID: 21427226
    7. Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition PMID: 20392696
    8. SLO3 is the principal potassium channel responsible for capacitation-induced hyperpolarization, and membrane hyperpolarization is crucial to the acrosome reaction. PMID: 20138882
    9. voltage and pH regulate a closed-open conformational change in a largely independent fashion PMID: 16940554
    10. increases in pH increase the fraction of more rapidly opening channels. PMID: 16940555
    11. native current observed in sperm is indeed carried by Slo3 channels. PMID: 19338774
    12. results argue that, for native mouse Slo3 channels, the beta4 subunit must be considered as a potential interaction partner and, furthermore, that KCNMB subunits may have functions unrelated to regulation of the Slo1 alpha subunit PMID: 19578543

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily
  • 組織特異性：
    Testis-specific. Mainly expressed in spermatocytes.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 国产精品高潮呻吟av久久无吗| 亚洲日本乱码在线观看| 亚洲 欧美 动漫 少妇 自拍| 无码av专区丝袜专区| 亚洲国产精品嫩草影院| 亚洲色成人网站www永久四虎| 香蕉午夜福利院| 国产视频亚洲精品视频| 热99re久久国超精品首页| 免免费国产aaaaa片| 粗大的内捧猛烈进出在线视频| 国产精品沙发午睡系列| 亚在线观看免费视频入口| 亚洲欧美日韩综合久久| 无码午夜人妻一区二区不卡视频| 国产精品福利视频导航| 久久久久无码国产精品不卡| 香港三级日本三级a视频| 国产熟妇另类久久久久久| 四虎成人精品永久网站| 国产女人被狂躁到高潮小说| 老湿机69福利区18禁网站| 菠萝菠萝蜜午夜视频在线播放观看 | 久久aaaa片一区二区| 成人乱人伦视频在线观看| 好男人资源在线www免费| 国产精品嫩草影院入口一二三| 波多野结av衣东京热无码专区| 欧美人牲口杂交在线播放免费| 国产成人美女裸体片免费看| 国产 日韩 中文字幕 制服| 日本一卡2卡3卡4卡无卡免费网站| 色欲av伊人久久大香线蕉影院| 天堂а√中文最新版在线| 曰的好深好爽免费视频网站| 精品无码一区二区三区av| 亚洲性无码av在线欣赏网| 久久久久国产精品人妻aⅴ四季| 欧美精品一国产成人综合久久 | 蜜桃一区二区三区| 亚洲精品久久久久久成人|