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  4. Recombinant Mouse Pikachurin (Egflam), partial

Recombinant Mouse Pikachurin (Egflam), partial

  • 中文名稱：
    小鼠Egflam重組蛋白
  • 貨號：
    CSB-YP706317MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Egflam重組蛋白
  • 貨號：
    CSB-EP706317MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Egflam重組蛋白
  • 貨號：
    CSB-EP706317MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Egflam重組蛋白
  • 貨號：
    CSB-BP706317MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Egflam重組蛋白
  • 貨號：
    CSB-MP706317MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Egflam
  • Uniprot No.：
  • 別名：
    EgflamPikachurin; EGF-like; fibronectin type-III and laminin G-like domain-containing protein; Nectican
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.
  • 基因功能參考文獻：
    1. Pikachurin Protein Required for Increase of Cone Electroretinogram B-Wave during Light Adaptation PMID: 26091521
    2. data suggest the existence of post-translational cleavage of pikachurin protein as well as the extracellular localization of cleaved protein specifically by retinal cells PMID: 23226524
    3. These results indicate that pikachurin interactions with alpha-dystroglycan and its localization at the photoreceptor ribbon synapse require normal glycosylation of alpha-dystroglycan. PMID: 21129441
    4. Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization. PMID: 20682766
  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix. Cell junction, synapse, synaptic cleft. Cell junction, synapse, presynaptic active zone. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells (PubMed:18641643). Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals (PubMed:18641643).
  • 組織特異性：
    Expressed in the outer plexiform layer (first synaptic region) but not in the inner plexiform layer (second synaptic region) of the retina (at protein level). Strongly expressed in the photoreceptor layer of the retina. Moderately expressed in pineal glan
  • 數據庫鏈接：


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