在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Pachytene checkpoint protein 2 homolog (Trip13)

Recombinant Mouse Pachytene checkpoint protein 2 homolog (Trip13)

  • 中文名稱：
    小鼠Trip13重組蛋白
  • 貨號：
    CSB-YP664934MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Trip13重組蛋白
  • 貨號：
    CSB-EP664934MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Trip13重組蛋白
  • 貨號：
    CSB-EP664934MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Trip13重組蛋白
  • 貨號：
    CSB-BP664934MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Trip13重組蛋白
  • 貨號：
    CSB-MP664934MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Trip13
  • Uniprot No.：
  • 別名：
    Trip13; Pch2; Pachytene checkpoint protein 2 homolog; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-432
  • 氨基酸序列
    MDEAVGDLKQ ALPCVAESPA VHVEVLQRSG STAKKEDIKS SVYRLLNRHN IVFGDYVWTE FDDPFLSRNV QSVSIVDTEL KAKDPQPIDL SACTIALHIF QLNEEGPSSE NLDEETENII AASHWVLPAA EFHGLWDSLV YDVEVKSHLL DYVMTTVLFS DKNVDSNLIT WNRVVLLHGP PGTGKTSLCK ALAQKLTIRL SSRYRYGQLI EINSHSLFSK WFSESGKLVT KMFQKIQDLI DDKEALVFVL IDEVESLTAA RNACRAGAEP SDAIRVVNAV LTQIDQIKRH SNVVILTTSN ITEKIDVAFV DRADIKQYIG PPSAAAIFKI YLSCLEELMK CQIIYPRQQL LTLRELEMIG FIENNVSKLS LLLSEISRKS EGLSGRVLRK LPFLAHALYI QAPSVTIEGF LQALSLAVDK QFEEKKKLSA YV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation.
  • 基因功能參考文獻：
    1. In all, these studies suggest that insufficient TRIP13 increased the susceptibility of damaged tubular epithelial cells to progress towards apoptotic cell death. PMID: 28256593
    2. TRIP13 ubiquitinates and degrades the checkpoint surveillance protein MAD2 via activating Akt signaling pathway, leading to weakened checkpoint surveillance and consequent tumorigenic aneuploidy and drug resistance in MM. PMID: 28157697
    3. TRIP13-deficient spermatocytes also progress to an H1t-positive stage if ATM activity is attenuated by hypomorphic mutations in Mre11 or Nbs1 or by elimination of the ATM-effector kinase CHK2 PMID: 25768017
    4. TRIP13 promotes error-prone non-homologous end joining and induces chemoresistance in head and neck cancer. PMID: 25078033
    5. TRIP13 is required for recombination and normal higher-order chromosome structure during meiosis. PMID: 20711356
    6. results demonstrate that in mice, the primary meiotic function of TRIP13 is in recombination itself PMID: 17696610

    顯示更多

    收起更多

  • 蛋白家族：
    AAA ATPase family, PCH2 subfamily
  • 組織特異性：
    Widely expressed, including in testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 激情综合五月丁香亚洲| 国产亚洲无线码一区二区| 色欲精品国产一区二区三区av| 久久精品国产首页027007| 自拍偷亚洲产在线观看| 无码加勒比一区二区三区四区| 性xxxx视频播放免费| www.-级毛片线天内射视视| 夜晚被公侵犯的人妻深田字幕| 欧美另类 自拍 亚洲 图区| 狠狠躁天天躁中文字幕| 西西人体444www大胆无码视频 | 欧美日本国产va高清cabal| 狠狠色噜噜狠狠色综合久| 亚洲超清无码制服丝袜无广告 | 免费观看性行为视频的网站 | 亚洲一线二线三线品牌精华液久久久 | 精品国产偷窥一区二区| 精品国产乱码久久久久久夜深人妻| 成人影院永久免费观看网址| 国产免费高清69式视频在线观看| 国产亚洲成av人片在线观黄桃| 欧美午夜理伦三级在线观看| 美女粉嫩饱满的一线天mp4| 欧美人与动牲交免费观看| 国产成人久久av免费高潮| 777奇米四色成人影视色区| h漫全彩纯肉无码网站| 四虎国产精品永久在线观看| 性色欲情网站iwww| 国产精品美女久久久久久2021| 亚洲成av人片在线播放无码| 国模大胆一区二区三区| 久久综合97丁香色香蕉| 精品国产自在精品国产精华天| 国产精品欧美久久久久久日本一道| 香蕉午夜福利院| 韩国无码色视频在线观看| 激情爆乳一区二区三区| 西西人体44www大胆无码| 久久国产精品国产四虎90后|