在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Ornithine decarboxylase antizyme 1 (Oaz1)

Recombinant Mouse Ornithine decarboxylase antizyme 1 (Oaz1)

  • 中文名稱：
    小鼠Oaz1重組蛋白
  • 貨號：
    CSB-YP016245MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Oaz1重組蛋白
  • 貨號：
    CSB-EP016245MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Oaz1重組蛋白
  • 貨號：
    CSB-EP016245MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Oaz1重組蛋白
  • 貨號：
    CSB-BP016245MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Oaz1重組蛋白
  • 貨號：
    CSB-MP016245MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Oaz1
  • Uniprot No.：
  • 別名：
    Oaz1; Oaz; Ornithine decarboxylase antizyme 1; ODC-Az
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-227
  • 氨基酸序列
    VKSSLQRIL NSHCFAREKE GDKRSATLHA SRTMPLLSQH SRGGCSSESS RVALNCCSNL GPGPRWCSDV PHPPLKIPGG RGNSQRDHSL SASILYSDER LNVTEEPTSN DKTRVLSIQS TLTEAKQVTW RAVWSGGGLY IELPAGPLPE GSKDSFAALL EFAEEQLQAD HVFICFPKNR EDRAALLRTF SFLGFEIVRP GHPLVPKRPD ACFMVYTLER EDPGEED
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
  • 基因功能參考文獻：
    1. Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ). PMID: 26093026
    2. we have generated transgenic mice overexpressing mouse antizyme 1 gene under its own regulatory sequences PMID: 24174210
    3. Ornithine decarboxylase antizyme expression reduces tumor incidence, multiplicity and size even in the absence of p53. PMID: 23222816
    4. The activity of AZ1 was low in the virgin and involuting stages, but increased markedly during late pregnancy and early lactation. PMID: 19997757
    5. Testosterone treatment enhanced AZ1 and N1-SSAT mRNA levels in a time-dependent manner PMID: 12709396
    6. antizyme and glycosaminoglycans have roles in polyamine transport PMID: 16263714
    7. Az-1 has a central and meaningful role in modulation of polyamine homeostasis, and in regulating cellular proliferation and transformation properties. PMID: 16568078
    8. required for the proper formation of forebrain and hindbrain midline structures PMID: 17524391
    9. The data-driven docking results suggest that both proteins occupy the same binding site on Az1, with Az1 binding within a large groove in antizyme inhibitor (AzI) and Ornithine Decarboxylase (ODC). PMID: 19465028
    10. antizyme expression requires programmed, ribosomal frameshifting PMID: 7813017

    顯示更多

    收起更多

  • 蛋白家族：
    ODC antizyme family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲精品国产suv| 玩弄放荡人妻少妇系列| 亚洲裸男自慰gv网站| 人妻精品无码一区二区三区| 熟妇人妻无码xxx视频| 日韩人妻潮喷中文在线视频 | 51精品国产人成在线观看| 久久青草费线频观看| 亚洲欧美中文日韩在线视频一| 国产亚洲tv在线观看| 久久久久久久综合日本| 日日噜噜夜夜狠狠va视频v| 老司机午夜福利视频| 亚洲精品欧美精品日韩精品| 欧美人与动牲交免费观看网 | 国产超碰人人做人人爱ⅴa| 8av国产精品爽爽ⅴa在线观看| 97se狠狠狠狠狼鲁亚洲综合色| 涩欲国产一区二区三区四区| 99精品视频九九精品视频| 在线天堂新版最新版在线8| 欧美熟妇乱子伦xx视频| 亚洲综合久久一本久道| 狠狠综合久久av一区二区| 国内大量揄拍人妻在线视频| 337p日本大胆欧美裸体艺术| 色综合久久久无码网中文| 四虎国产精品永久在线| 久久综合色一综合色88| 综合偷自拍亚洲乱中文字幕| 欧美日韩精品一区二区在线播放| 亚洲精品乱码久久久久久蜜桃不卡| 2018高清日本一道国产-在| 特大黑人娇小亚洲女| 亚洲中文字幕无码一区在线| 国产午夜片无码区在线观看爱情网 | 在线精品国产成人综合| 熟妇人妻午夜寂寞影院| 又爽又黄无遮挡高潮视频网站| 人妻少妇久久久久久97人妻 | 国产成人a无码短视频|