Recombinant Mouse Netrin-G1 (Ntng1)

中文名稱：

小鼠Ntng1重組蛋白
貨號(hào)：

CSB-YP837148MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

小鼠Ntng1重組蛋白
貨號(hào)：

CSB-EP837148MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ntng1重組蛋白
貨號(hào)：

CSB-BP837148MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

小鼠Ntng1重組蛋白
貨號(hào)：

CSB-MP837148MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ntng1
Uniprot No.：

Q8R4G0
別名：

Ntng1; Kiaa0976; Lmnt1; Netrin-G1; Laminet-1
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

19-510
氨基酸序列

VM QPYLFVWGHY DVCKSLIYTE EGKVWDYTAC QPESTDMTKY LKVKLDPPDI TCGDPPESFC AMGNPYMCNN ECDASTPELA HPPELMFDFE GRHPSTFWQS ATWKEYPKPL QVNITLSWSK TIELTDNIVI TFESGRPDQM ILEKSLDYGR TWQPYQYYAT DCLHAFHMDP KSVKDLSQHT VLEIICTEEY STGYSTNSKI IHFEIKDRFA FFAGPRLRNM ASLYGQLDTT KKLRDFFTVT DLRIRLLRPA VGEIFVDELH LARYFYAISD IKVRGRCKCN LHATSCLYDN SKLTCECEHN TTGPDCGKCK KNYQGRPWSP GSYLPIPKGT ANTCIPSISS IGNCECFGHS NRCSYIDLLN TVICVSCKHN TRGQHCELCR LGYFRNASAQ LDDENVCIEC YCNPLGSIHD RCNGSGFCEC KTGTTGPKCD ECLPGNSWYY GCQPNVCDNE LLHCQNGGTC QNNVRCACPD AYTGILCEKL RCEEAGSCGS
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
基因功能參考文獻(xiàn)：
1. findings support a crucial role for netrin-G1 in dissociable neural circuits for the modulation of emotion-related behaviors, and provide genetic models for investigating the mechanisms underlying the dissociation. PMID: 27345935
2. Pre-synaptic netrin-G1 and netrin-G2 diversify the complexity of vertebrate behaviors and differentially regulate post-synaptic properties. PMID: 26746425
3. netrin-G/NGL interactions differentially control synaptic plasticity in distinct circuits via retrograde signaling mechanisms PMID: 25411505
4. The complementary expression patterns of Ntng1 and Ntng2 are determined by transcriptional cis-regulatory elements widely scattered in these loci. PMID: 24642214
5. selectively expressed in distinct neuronal subsets that include populations in forebrain, midbrain, hindbrain, spinal cord, and spinal ganglia PMID: 11906208
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亞細(xì)胞定位：

Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
組織特異性：

Expression is restricted primarily to neurons of the CNS, particularly in the dorsal thalamus, olfactory bulb and inferior colliculus. Isoform 1A and isoform 1D are the major products in adult brain.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:80883

STRING: 10090.ENSMUSP00000072397

UniGene: Mm.39262