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Recombinant Mouse NEDD8 ultimate buster 1 (Nub1)

  • 中文名稱:
    小鼠Nub1重組蛋白
  • 貨號:
    CSB-YP016141MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Nub1重組蛋白
  • 貨號:
    CSB-EP016141MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Nub1重組蛋白
  • 貨號:
    CSB-EP016141MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Nub1重組蛋白
  • 貨號:
    CSB-BP016141MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Nub1重組蛋白
  • 貨號:
    CSB-MP016141MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Nub1
  • Uniprot No.:
  • 別名:
    Nub1; Nyren18; NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Protein BS4
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-614
  • 氨基酸序列
    MAQKKYLQAK LTQFLREDRI QLWKPPYTKE NKEVGLAVKD LAKKYSERLE CCENEVENII EEIRRKAIER GTGNEHYRTT GIATIEVFLP PRLRKHDKKS LLETRLHVTG RDLRCQIAET FGFQENYIKI VINKKQLQLG KSLEEQGVTH NVKAMVLELK QSEEDVRKNL QLEEEEQNEA ELKERRIQRT KRGLEILAER AEMVVDPETM PYLDIANQTG RSLRIPPAER KALMLAMGYH EKGRAFLKRK EYGIALPCLL DADRYFCECK ELLDTVDNYA VLQLDIVWCY FRLEQLECLD DAEKKLNLAQ KCFKNCYGEN HQRLVHIKGN CGKEKVLFLR LYLLQGIQNY HSGNGEEARE YLNKARQLFK ELYIDPSKVH NLLQLGFTAQ EARLGLRACD GNVDHAATHI SNRREELAQI RKEEKEKRRR RLENVNTLRG MGYSTQAAKQ ALHQARGNLD DALKVLLSNP HMWWLQDADP ENNSRQASPS QESINQLVYM GFDTVVAEAA LRVFGGNVQL AAQTLAHHGG SLPPDLQFSG EDSSPTPSTS PSDSAGTSSA STDEDMETEA VNEILEDIPE HEEDYLDSTL EDEEVIIAEY LSYVESISSA AKNN
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation.
  • 基因功能參考文獻:
    1. These results suggest that increased levels of NUB1 play a potential role in degradation of detergent-insoluble alpha-synuclein in vivo, although it is insufficient to degrade abnormal alpha-synuclein in Lewy body disease model mice. PMID: 26797281
    2. NUB1L suppresses atypical neddylation and promotes the degradation of misfolded proteins by the proteasome PMID: 26260793
    3. NUB1 has a splicing variant, NUB1L, which regulates the NEDD8 conjugation system PMID: 12816948
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:


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