在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse N-alpha-acetyltransferase 10 (Naa10)

Recombinant Mouse N-alpha-acetyltransferase 10 (Naa10)

  • 中文名稱：
    小鼠Naa10重組蛋白
  • 貨號(hào)：
    CSB-YP889880MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Naa10重組蛋白
  • 貨號(hào)：
    CSB-EP889880MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Naa10重組蛋白
  • 貨號(hào)：
    CSB-EP889880MO-B
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Naa10重組蛋白
  • 貨號(hào)：
    CSB-BP889880MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Naa10重組蛋白
  • 貨號(hào)：
    CSB-MP889880MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Naa10
  • Uniprot No.：
  • 別名：
    Naa10; Ard1; Ard1a; Te2; N-alpha-acetyltransferase 10; EC 2.3.1.255; N-terminal acetyltransferase complex ARD1 subunit homolog A; NatA catalytic subunit Naa10
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-235
  • 氨基酸序列
    MNIRNARPED LMNMQHCNLL CLPENYQMKY YFYHGLSWPQ LSYIAEDENG KIVGYVLAKM EEDPDDVPHG HITSLAVKRS HRRLGLAQKL MDQASRAMIE NFNAKYVSLH VRKSNRAALH LYSNTLNFQI SEVEPKYYAD GEDAYAMKRD LTQMADELRR HLELKEKGKH MVLAALENKA ENKGNVLLSS GEACREEKGL AAEDSGGDSK DLSEVSETTE STDVKDSSEA SDSAS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. Acetylates amino termini that are devoid of initiator methionine. The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development. Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX. Acetylates HIST1H4A. Acts as a negative regulator of sister chromatid cohesion during mitosis.
  • 基因功能參考文獻(xiàn)：
    1. Negative regulation of Naa10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation. PMID: 27910960
    2. The lethal Ogden syndrome-associated mutation of Naa10p disrupts its binding to the imprinting control region of H19 and Dnmt1 recruitment. PMID: 28943313
    3. NAA10 acts as a guard ensuring balanced osteogenesis by fine-tuning Runx2 signalling in a feedback manner. PMID: 25376646
    4. ARD1 has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA. PMID: 25341044
    5. mARD1A(225) may be a novel upstream target that blocks VEGFA expression and tumor-related angiogenesis. PMID: 20194889
    6. Biochemical analysis demonstrated that mNAT1 and its evolutionarily conserved co-subunit, mARD1, assemble to form a functional acetyltransferase. PMID: 12888564
    7. Mouse ortholog (225) of ARD1 strongly decreased the level of hypoxia inducible factor (HIF)-1 alpha and increased the extent of acetylation, whereas mARD1(235) variants had a much weaker effect on HIF-1 alpha stability and acetylation. PMID: 16376303
    8. These results indicate that ARD1(235) and ARD1(225) isoforms may have different activities and function in different subcellular compartments of mammalian cells. PMID: 17161380

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Acetyltransferase family, ARD1 subfamily
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 亚洲熟妇中文字幕五十中出| 国内一区二区三区香蕉aⅴ| 97无码免费人妻超级碰碰碰碰| 在线精品自偷自拍无码中文| 国产日韩一区二区三免费高清| 好紧好爽好湿别拔出来视频男男| 一本久道久久综合久久爱| 久久精品国产2020| 蜜臀av夜夜澡人人爽人人| 免费观看激色视频网站| 天天影视网天天综合色| av无码av不卡一区二区| 久久超乳爆乳中文字幕| 国产精品久久福利网站| 亚洲综合图色40p| 波多野结衣久久一区二区| 亚洲一区日韩高清中文字幕亚洲| 亚洲国产欧美日韩在线人成| 久久久久久亚洲精品| 偷看少妇自慰xxxx| 中文字幕漂亮人妻熟睡中被公侵犯 | 丁香五月网久久综合| 中国6一12呦女精品| 女人和拘做爰正片视频| 成人精品视频在线观看不卡| 偷柏自拍亚洲综合在线| 成人爽a毛片免费啪啪| 在线观看黄a∨免费无毒网站| 少妇被黑人4p到惨叫欧美人| 人人爽人人爱| 国产肥熟女视频一区二区三区| 人人爽人人爽人人片av免费| 国产亚洲精品a片久久久| 国产麻豆天美果冻无码视频| 久久久综合九色综合88| 亚洲精品综合欧美一区二区三区| 亚洲aⅴ男人的天堂在线观看| 国产乱妇乱子在线播放视频| 西西艺术人像摄影| 国产午夜福利精品久久2021| 亚洲∧v久久久无码精品|