在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Metabotropic glutamate receptor 4 (Grm4), partial

Recombinant Mouse Metabotropic glutamate receptor 4 (Grm4), partial

  • 中文名稱：
    小鼠Grm4重組蛋白
  • 貨號(hào)：
    CSB-YP731564MO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Grm4重組蛋白
  • 貨號(hào)：
    CSB-EP731564MO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Grm4重組蛋白
  • 貨號(hào)：
    CSB-EP731564MO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Grm4重組蛋白
  • 貨號(hào)：
    CSB-BP731564MO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Grm4重組蛋白
  • 貨號(hào)：
    CSB-MP731564MO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Grm4; Gprc1d; Mglur4Metabotropic glutamate receptor 4; mGluR4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
  • 基因功能參考文獻(xiàn)：
    1. This immuno-electron microscopic studies suggest that pre-synaptic metabotropic glutamate receptor 4 (mGluR4) in striatal glutamatergic terminals is expressed almost exclusively in cortical boutons to subserve regulatory influences upon a large contingent of corticostriatal terminals that preferentially target putative "indirect" pathway striatal projection neurons in mice. PMID: 26832920
    2. Study assessed the actions of the first mGlur4-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia; results suggest that the interplay between mGlu4 and GABAB receptors may become the basis for a novel therapy for schizophrenic patients with predomination of positive symptoms PMID: 26769224
    3. A functional hetero-complex is formed with mGluR2 and mGluR4 in central nervous system. PMID: 24381270
    4. mGluR4-/- mice show increased long-term potentiation in hippocampal CA1 region and improved maze learning. PMID: 23714430
    5. data support a role for mGluR4 signaling in acquisition of fear learning and memory. PMID: 22884897
    6. The expression of mGluR4 is down-regulated in the cardiomyocyte differentiation of embryonic stem cells. PMID: 22927070
    7. These data indicate that effects of mGluR4 on sensorimotor function and measures of anxiety, but not cued fear conditioning, are critically modulated by sex and age. PMID: 22227508
    8. A role for mGlu4 was found whereby simultaneous activation with GABA(A) receptors acts to amplify glutamate release at parallel fiber-Purkinje cell synapses. PMID: 22145864
    9. These data indicate that activation of mGlu4 receptors limit the development of brain damage after permanent or transient focal ischemia PMID: 21157475
    10. Grm4 modulates adaptive immunity and restrains neuroinflammation. PMID: 20657581
    11. The most intense mGluR4 labelling was in the cerebellar cortex, basal ganglia, the sensory relay nuclei of the thalamus, and some hippocampal areas. Immunolabelling was most intense in presynaptic active zones. PMID: 11906782
    12. These data suggest that mGlu4 receptor enhancers are promising drugs for the treatment of medulloblastomas. PMID: 16899734
    13. Our results suggest a role for mGluR1 in promoting seizure susceptibility as well as for mGluR4 to counteract excitatory activity and seizure-associated vulnerability of hippocampal neurons. PMID: 17446080

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 3 family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 欧美熟妇另类久久久久久不卡| 久久国产午夜精品理论片34页| 欧美成 人 网 站 免费| 大香网伊人久久综合网2018| 免费观看黄网站| 妺妺窝人体色www聚色窝仙踪| 四虎永久免费地址入口| 亚洲中文有码字幕日本| 亚洲影院丰满少妇中文字幕无码 | 无码国产精品一区二区免费模式| 欧洲亚洲色一区二区色99| 亚洲人成人无码网www国产| 国产情侣草莓视频在线| 国产精品嫩草99av在线| 亚洲 熟女 久久 国产| 亚洲免费观看在线视频| 久久99久久99精品中文字幕| 少妇扒开双腿让我看个够| 野外做受又硬又粗又大视频√ | 伊人久久大香线蕉av成人| 99久久婷婷国产综合精品青草免费| 日本道色综合久久影院| 狠狠色噜噜狠狠狠狠蜜桃| 少妇被又大又粗又爽毛片久久黑人| 女人18毛片水真多| 国产精品成人片在线观看| 野花社区www视频最新资源| 亚洲色欲色欱www在线| 精品无码一区二区三区爱欲| 午夜人妻理论片天堂影院| 国产裸体xxxx视频| 非洲人与性动交ccoo| 国产亚洲日本精品成人专区| 色综合a怡红院怡红院| 扒开女人内裤猛进猛出免费视频| 高清欧美性猛交xxxx黑人猛交| 亚洲精品无码av中文字幕电影网站 | 色老久久精品偷偷鲁| 欧美精品videossex另类日本| 国产在线观看www污污污| 99精品电影一区二区免费看|