在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Matrilin-3 (Matn3)

Recombinant Mouse Matrilin-3 (Matn3)

  • 中文名稱：
    小鼠Matn3重組蛋白
  • 貨號：
    CSB-YP013522MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Matn3重組蛋白
  • 貨號：
    CSB-EP013522MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Matn3重組蛋白
  • 貨號：
    CSB-EP013522MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Matn3重組蛋白
  • 貨號：
    CSB-BP013522MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Matn3重組蛋白
  • 貨號：
    CSB-MP013522MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Matn3
  • Uniprot No.：
  • 別名：
    Matn3Matrilin-3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    28-481
  • 氨基酸序列
    APG RLARASVRRL GTRVPGGSPG HLSALATSTR APYSGGRGAG VCKSRPLDLV FIIDSSRSVR PLEFTKVKTF VSRIIDTLDI GATDTRVAVV NYASTVKIEF QLNTYSDKQA LKQAVARITP LSTGTMSGLA IQTAMEEAFT VEAGARGPMS NIPKVAIIVT DGRPQDQVNE VAARARASGI ELYAVGVDRA DMESLKMMAS KPLEEHVFYV ETYGVIEKLS ARFQETFCAL DQCMLGTHQC QHVCVSDGDG KHHCECSQGY TLNADGKTCS AIDKCALSTH GCEQICVNDR NGSYHCECYG GYALNADRRT CAALDKCASG THGCQHICVN DGAGSHHCEC FEGYTLNADK KTCSVRNKCA LGTHGCQHIC VSDGAVAYHC DCFPGYTLND DKKTCSDIEE ARSLISIEDA CGCGATLAFQ EKVSSHLQKL NTKLDNILKK LKVTEYGQVH R
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
  • 基因功能參考文獻：
    1. Data show that hand osteoarthritis (HOA)-related matrilin-3 mutation (T298M) leads to a high expression level of growth arrest DNA damage-inducible gene 153 (GADD153) PMID: 26499313
    2. MATN3 plays a regulatory role in cartilage homeostasis due to its capacity to induce IL-1Ra, upregulate gene expression of major cartilage matrix components, and downregulate the expression of OA-associated matrix-degrading proteinases in chondrocytes. PMID: 22967398
    3. MATN3 may have the inherent ability to inhibit premature chondrocyte hypertrophy by suppressing BMP-2/Smad1 activity PMID: 25331953
    4. study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH/MED spectrum and subsequent care of PSACH/MED patients PMID: 24312420
    5. Lack of COMP and matrilin 3 leads to increased deposition of TIMP-3, which causes partial inactivation of matrix metalloproteinases in bone, including MMP-13. PMID: 22378539
    6. matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen fibrils PMID: 20077500
    7. potential of matrilin-3 to modulate gene expression profile of primary chondrocytes; tested matrilin3-dependent induction of pro-inflammatory cytokines, inducible nitric oxide synthetase & cyclooxygenase-2, MMP1, -3 & -13, & matrilin-3 itself PMID: 19840795
    8. Expression of matrilin-3 during maturation of mouse skeletal tissues PMID: 12009334
    9. To assess the function of matrilin-3 during skeletal development, we have generated Matn-3 null mice; phenotypes of multiple epiphyseal dysplasia disorders are not caused by the absence of matrilin-3 in cartilage ECM. PMID: 14749384
    10. Matrilin-3 can be considered as an interface component, capable of interconnecting macromolecular networks PMID: 16287859
    11. The lack of Matn3 does not lead to postnatal chondrodysplasia but accounts for higher incidence of osteoarthritis. PMID: 16877353
    12. a matn3 mutation causes decreased chondrocyte proliferation and dysregulated apoptosis leading to epiphyseal dysplasia PMID: 17517694

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 組織特異性：
    Strongly expressed in growing skeletal tissue such as epiphyseal growth plate or in bone undergoing growth and remodeling. In the bone, actively synthesized in osteoblasts and osteocytes. Expressed in cartilage of sternum, femur, vertebrae, trachea, artic
  • 數據庫鏈接：


主站蜘蛛池模板： 中文字幕卡二和卡三的视频| 亚洲 小说区 图片区 都市| 999国内精品永久免费视频| 国产乱子伦精品免费无码专区| 美女mm131午夜福利在线| 亚洲一区二区三区无码影院| 亚洲精品中文字幕乱码三区| 国产suv精品一区二人妻| 欧美日激情日韩精品嗯| 亚洲人成网站18禁止中文字幕| 韩国日本三级在线观看| 久久精品国产精品青草| 久久三级中文欧大战字幕| 男人边吃奶边做好爽免费视频| 男女性色大片免费网站| 亚洲欧美精品suv| 他用舌头给我高潮喷水在线| 奶头好大狂揉60分钟视频| 亚洲精品亚洲人成人网| 久久久久77777人人人人人| 日产精品中文一区二区三区| 熟妇高潮喷沈阳45熟妇高潮喷| 久久天天躁狠狠躁夜夜av| 在线观看成人年视频免费| 亚洲一区二区三区国产精品无码| 国产男女猛烈无遮挡免费网站 | 伊人亚洲综合影院首页| 丰满人妻被黑人中出849| 视频分类 国内精品| 欧美v亚洲v日韩v最新在线| 国产办公室无码视频在线观看| 亚洲国产综合在线区尤物| 鲁丝一区二区三区免费| 亚洲国产精品不卡av在线| 日本免费人成在线观看网站| 色天使久久综合网天天| 亚洲国产精品18久久久久久| 国产欧美日韩视频一区二区三区 | 日韩精品专区在线影院重磅| 乱中年女人伦av三区| 人人妻人人澡人人爽欧美一区九九 |