在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse MAP kinase-interacting serine/threonine-protein kinase 2 (Mknk2)

Recombinant Mouse MAP kinase-interacting serine/threonine-protein kinase 2 (Mknk2)

  • 中文名稱：
    小鼠Mknk2重組蛋白
  • 貨號：
    CSB-YP804943MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mknk2重組蛋白
  • 貨號：
    CSB-EP804943MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mknk2重組蛋白
  • 貨號：
    CSB-EP804943MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mknk2重組蛋白
  • 貨號：
    CSB-BP804943MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mknk2重組蛋白
  • 貨號：
    CSB-MP804943MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Mknk2; Mnk2MAP kinase-interacting serine/threonine-protein kinase 2; EC 2.7.11.1; MAP kinase signal-integrating kinase 2; MAPK signal-integrating kinase 2; Mnk2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-459
  • 氨基酸序列
    MVQKRTAELQ GFHRSFKGQN PFELAFSLDL AQHRDSDFSP QCEARPDMPS SQPIDIPDAK KRGRKKKRCR ATDSFSGRFE DVYQLQEDVL GEGAHARVQT CVNLITNQEY AVKIIEKQLG HIRSRVFREV EMLYQCQGHR NVLELIEFFE EEDRFYLVFE KMRGGSILSH IHRRRHFNEL EASVVVQDVA SALDFLHNKG IAHRDLKPEN ILCEHPNQVS PVKICDFDLG SGIKLNGDCS PISTPELLTP CGSAEYMAPE VVEAFSEEAS IYDKRCDLWS LGVILYILLS GYPPFVGHCG SDCGWDRGEA CPACQNMLFE SIQEGKYEFP DKDWSHISFA AKDLISKLLV RDAKQRLSAA QVLQHPWVQG CAPENTLPTP LVLQRNSCAK DLTSFAAEAI AMNRQLAQCE EDAGQDQPVV IRATSRCLQL SPPSQSKLAQ RRQRASLSAT PVVLVGDRA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A-inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Enhances the formation of EIF4F complex in pachytene spermatocytes, thus promoting mRNA translation during spermatogenesis. Displays a high basal kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal.
  • 基因功能參考文獻：
    1. MNK2 plays a role in adipogenesis and/or lipogenesis and in macrophage biology PMID: 27087055
    2. Mnk2a directly interacts with and translocates p38alpha-MAPK into the nucleus. Alternatively, Mnk2b does not activate p38-MAPK. PMID: 24726367
    3. eIF4E phosphorylation is enhanced by Rapamycin, which activates Mnk2a PMID: 23831578
    4. Data indicate that MNK2 plays a unique role, not shared by its closest paralog MNK1, in limiting protein translation through its negative effect on eIF4G Ser1108 phosphorylation and p70S6K activation. PMID: 22337810
    5. MAP kinase-interacting kinase 1 and 2 activity enhances formation of the EIF-4F complex in pachytene spermatocytes but not in round spermatids. PMID: 20574055

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus, PML body.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 組織特異性：
    Ubiquitously expressed in all tissues examined, with high levels in skeletal muscle and low levels in brain.
  • 數據庫鏈接：


主站蜘蛛池模板： 无码专区—va亚洲v天堂麻豆| 熟妇人妻系列aⅴ无码专区友真希| 国产色视频一区二区三区| 自慰系列无码专区| 国产乱人伦偷精品视频下| 亚洲精品久久久久一区二区三区| 中文字幕人成无码人妻综合社区| 一本色道久久88综合日韩精品| 99热国产这里只有精品9| 久久不见久久见免费影院视频| 国产一区二区三区在线观看免费| 美女又黄又免费的视频| 熟睡中被义子侵犯在线播放| 一本大道东京热无码视频| 亚洲欧美色中文字幕在线| 免费纯肉3d动漫无码网站| 特殊重囗味sm在线观看无码| 亚洲精品无码专区在线| 欧美mv日韩mv国产网站| 中文字幕av无码不卡| а√天堂www在线а√天堂资源| 性亚洲videofree高清| 欧美老妇与zozoz0交| 24小时日本在线www免费的| 97成人精品区在线播放| 波多野结衣办公室33分钟| 色综合欧美在线视频区| 日韩精品一区二区三区影院 | 骚虎成人免费99xx| 乱中年女人伦av三区| 俄罗斯美女真人性做爰| 国内精品久久久久影院中文字幕 | 蜜臀av性久久久久蜜臀aⅴ麻豆| 久久久久国产综合av天堂| 欧美一区二区三区性视频| 国产精品亚洲а∨天堂123| 一本之道高清无码视频| 色婷婷五月综合久久| 国产精品久久久久久久伊一| 色噜噜狠狠狠综合曰曰曰| 熟妇人妻无码xxx视频 |