在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Lysosomal-trafficking regulator (Lyst), partial

  • 中文名稱:
    小鼠Lyst重組蛋白
  • 貨號(hào):
    CSB-YP013281MO
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Lyst重組蛋白
  • 貨號(hào):
    CSB-EP013281MO
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Lyst重組蛋白
  • 貨號(hào):
    CSB-EP013281MO-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Lyst重組蛋白
  • 貨號(hào):
    CSB-BP013281MO
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Lyst重組蛋白
  • 貨號(hào):
    CSB-MP013281MO
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Lyst
  • Uniprot No.:
  • 別名:
    Lyst; Bg; Chs1Lysosomal-trafficking regulator; Beige protein; CHS1 homolog
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Adapter protein that regulates and/or fission of intracellular vesicles such as lysosomes. Might regulate trafficking of effectors involved in exocytosis. In cytotoxic T-cells and natural killer (NK) cells, has role in the regulation of size, number and exocytosis of lytic granules. In macrophages and dendritic cells, regulates phagosome maturation by controlling the conversion of early phagosomal compartments into late phagosomes. In macrophages and dendritic cells, specifically involved in TLR3- and TLR4-induced production of pro-inflammatory cytokines by regulating the endosomal TLR3- TICAM1/TRIF and TLR4- TICAM1/TRIF signaling pathways.
  • 基因功能參考文獻(xiàn):
    1. Lyst as a specific regulator of TLR3- and TLR4-mediated TRIF signaling pathways reveals how the regulation of the intracellular membrane trafficking network is functionally linked to specific TLR signaling pathways. PMID: 27881733
    2. results identify an association between oxidative damage to lipid membranes and the severity of Lyst-mutant phenotypes, revealing a new mechanism that contributes to pathophysiology involving LYST PMID: 20617205
    3. the Lyst(Ing3618 )allele could represent a new model for adult Chediak-Higashi syndrome with neurological impairment PMID: 16791600
    4. Apolipoprotein E (ApoE)-deficient beige mice have markedly reduced development of atherosclerotic lesions when fed a chow diet; expression of the beige mutation in all cell types involved in lesion development contributes to atheroprotection. PMID: 17982137
    5. The upregulation of LYST/Beige in infected cells functions as a host innate response to limit parasite growth. PMID: 18927622
    6. These results demonstrated that mutation of the Lyst gene can produce ocular features of human XFS (exfoliation syndrome) and suggested that LYST or LYST-interacting genes may contribute to XFS. PMID: 19029039

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Defects in Lyst are the cause of beige, an autosomal recessive disorder characterized by hypopigmentation, bleeding, immune cell dysfunction, abnormal intracellular transport to and from the lysosome, and giant inclusion bodies in a variety of cell types.
  • 亞細(xì)胞定位:
    Cytoplasm.
  • 組織特異性:
    Expressed in the heart, lung, liver, spleen, brain and in different immune cell types (purified B and T lymphocytes, bone marrow-derived macrophages and dendritic cells).
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 欧美老人巨大xxxx做受| 少妇人妻中文字幕污| 国产无套水多在线观看| 无码a∨高潮抽搐流白浆| 2018天天拍拍天天爽视频| 精品国产乱码一区二区三区| 2024av天堂手机在线观看| 中文字幕精品无码一区二区 | 午夜大片男女免费观看爽爽爽尤物 | 成 人片 黄 色 大 片| 午夜寂寞少妇aaa片毛片| 在线 | 麻豆国产传媒61国产免费| 午夜福利啪啪无遮挡免费| 精品无码久久久久国产电影| 久久精品国产99国产精2021 | 中文字字幕在线成人av电影| 香蕉av777xxx色综合一区| 日日躁夜夜躁白天躁晚上| 日韩精品一区二区av在线观看| 国产精品成人观看视频国产奇米| 国产熟女高潮视频| 强睡邻居人妻中文字幕| 亚洲国产精品久久久天堂麻豆宅男 | 色欲av亚洲情无码av蜜桃| 午夜人性色福利无码视频在线观看| 国产人妻人伦精品1国产盗摄| 国产乱人伦app精品久久| 中文午夜乱理片无码| 欧洲精品无码一区二区三区在线播放| 欧美专区另类专区在线视频| 国产精品久久久久9999| 日本中国内射bbxx| 思思99re6国产在线播放| 无尺码精品产品国产| 亚洲成a v人片在线观看| 久久久亚洲精华液精华液精华液| 夜晚被公侵犯的人妻深田字幕| 美女18禁一区二区三区视频| 亚洲成a人片在线不卡一二三区 | 四虎影库在线永久影院免费观看| 狠狠人妻久久久久久综合|