在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Long-chain fatty acid transport protein 4 (Slc27a4), partial

Recombinant Mouse Long-chain fatty acid transport protein 4 (Slc27a4), partial

  • 中文名稱：
    小鼠Slc27a4重組蛋白
  • 貨號：
    CSB-YP856293MO1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Slc27a4重組蛋白
  • 貨號：
    CSB-EP856293MO1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Slc27a4重組蛋白
  • 貨號：
    CSB-EP856293MO1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Slc27a4重組蛋白
  • 貨號：
    CSB-BP856293MO1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Slc27a4重組蛋白
  • 貨號：
    CSB-MP856293MO1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Slc27a4; Acsvl4; Fatp4; Long-chain fatty acid transport protein 4; FATP-4; Fatty acid transport protein 4; Arachidonate--CoA ligase; Long-chain-fatty-acid--CoA ligase; Solute carrier family 27 member 4; Very long-chain acyl-CoA synthetase 4; ACSVL4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Probably involved in fatty acid transport across the blood barrier. Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones.
  • 基因功能參考文獻：
    1. a spontaneous Fatp4/Scl27a4 splice site mutation in congenital ichthyosis PMID: 23226340
    2. FATP4 plays crucial roles in the development and maturation of both sebaceous and meibomian glands, as well as in the formation and composition of sebum PMID: 23271751
    3. A key role was demonstrated for FATP4 in oleic acide-induced GLP-1 secretion from the murine intestinal L cell in vitro and in vivo. PMID: 22871340
    4. even though hypoxia regulates the expression of FATP2 and FATP4 in human trophoblasts, mouse Fatp2 and Fatp4 are not essential for intrauterine fetal growth. PMID: 22028793
    5. FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of CC muscle cells. PMID: 21750264
    6. adipocyte-specific Fatp4 deficiency results in adipose hypertrophy and profound alterations in the metabolism of complex lipids. PMID: 21808061
    7. identification of critical role in skin and hair development PMID: 12697906
    8. Fatp4-null mice displayed features of a neonatally lethal restrictive dermopathy. Lipid analysis demonstrated a disturbed fatty acid composition of epidermal ceramides. PMID: 12821645
    9. role in fat absorption in early embryogenesis and suggests a novel requirement for function during development PMID: 14512415
    10. FATP4 exhibits intrinsic acyl-coa synthetase activity and is a high velocity enzyme relative to FATP1. PMID: 15653672
    11. Fatp4 in epidermal keratinocytes is essential for the maintenance of a normal epidermal structure. PMID: 16354193
    12. FATP4 drives fatty acid uptake indirectly by esterification. It is not a transporter protein involved in fatty acid translocation at the plasma membrane. PMID: 17062637
    13. in murine skin fibroblasts, FATP4 is the major enzyme producing very long chain fatty acid-CoA for lipid metabolic pathways PMID: 17522045
    14. Fatp4(-/-);Ivl-Fatp4(tg/+) mice and wild-type littermates displayed indistinguishable food consumption, growth, and weight gain on either low or high fat (Western) diets, with no differences in intestinal triglyceride (TG) absorption or fecal fat losses. PMID: 18843142

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Defects in Slc27a4 are the cause of wrinkle-free (wrfr) phenotype. It is a spontaneous, autosomal recessive mutation resulting in very tight, thick skin and is secondary characterized by severe breathing difficulties. Mice die shortly after birth. This phenotype is similar to human restrictive dermopathy, a very rare human genetic disorder.
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 組織特異性：
    Most abundantly expressed in small intestine, brain, kidney, liver, skin and heart. In small intestine, expressed at high levels on the apical side of mature enterocytes. Highly expressed by the epithelial cells of the visceral endoderm and localized to t
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： av蓝导航精品导航| 少妇高潮喷水久久久久久久久久| 五月花成人网| 欧美精品亚洲精品日韩专区va | 亚洲伊人久久精品酒店| 后入到高潮免费观看| r级无码视频在线观看| 最新国产精品拍自在线观看| 日本亚洲欧美日韩国产ay| 色婷婷亚洲一区二区综合| 美女视频黄频a免费| 日本护士毛茸茸高潮 | 六月丁香亚洲综合在线视频| 2021国产成人精品久久| 国产乱子伦农村xxxx| 国产情侣一区二区三区| 亚洲精品一品区二品区三区| 欧美大片欧美激情性色a∨在线| 无码人妻丰满熟妇啪啪欧美| 日本最大色倩网站www| 欧美毛多水多黑寡妇| 日本免费人成在线观看网站| 人妻换人妻a片爽麻豆| 久久成人影院精品777| 人人妻人人澡人人爽国产| 高潮好爽视频在线观看| 日韩无套无码精品| 性生交大片免费看| 少妇无码av无码专区线| 亚洲综合无码av一区二区三区| 中文字幕一区在线观看视频| 色噜噜狠狠色综合久夜色撩人| 在线亚洲高清揄拍自拍一品区 | 57pao成人国产永久免费视频| 精品国产小视频在线观看| 中文字幕av无码免费久久| 四库影院永久四虎精品国产 | 国产午夜福利短视频| 国产精品怡红院在线观看| 欧美国产日韩a欧美在线观看| 亚洲a∨无码男人的天堂|