在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Long-chain-fatty-acid--CoA ligase 4 (Acsl4), partial

In Stock
  • 貨號(hào):
    CSB-EP879427MO
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Arachidonate--CoA ligase Long-chain acyl-CoA synthetase 4
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    E.coli
  • 分子量:
    59.3 kDa
  • 表達(dá)區(qū)域:
    100-581aa
  • 氨基酸序列
    EILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs. Modulates prostaglandin E2 secretion.
  • 基因功能參考文獻(xiàn):
    1. studies have identified a novel substrate-induced posttranslational regulatory mechanism by which AA downregulates ACSL4 protein expression in hepatic cells. PMID: 24879802
    2. ACSL4 plays a tumor-suppressive role in gastric cancer. PMID: 26949059
    3. Report PPARdelta-mediated regulatory mechanism for ACSL4 expression in liver tissue and cultured hepatic cells. PMID: 25645621
    4. Sequence analysis of a 1.5-kb fragment of the Acsl4 promoter revealed the absence of a TATA box and the presence of many putative binding sites for transcription factors including Sp1 and CREB. PMID: 23376217
    5. Acsl4 is a phosphoprotein whose phosphorylation is hormone-dependent. PMID: 23159612
    6. These results indicate that the ACS4 protein specifically expressed in brain plays an important role in arachidonate metabolism and neuronal differentiation in the brain. PMID: 22366036
    7. the involvement of SHP2 activity in the regulation of the expression of the fatty acid-metabolizing enzyme ACSL4 PMID: 21903867

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane.
  • 蛋白家族:
    ATP-dependent AMP-binding enzyme family
  • 組織特異性:
    Abundant in steroidogenic tissues, also found in the kidney, brain and liver.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: av亚欧洲日产国码无码| 男女一边摸一边做爽爽| аⅴ资源天堂资源库在线| 麻豆人妻少妇精品无码专区| 在线亚洲欧美日韩精品专区| 亚洲欧美日韩国产成人一区| 免费人成小说在线观看网站| 久久久久久综合网天天| 亚洲日韩久热中文字幕| 亚洲人成77777在线播放网站| 人人狠狠综合久久亚洲爱咲| 337p粉嫩大胆色噜噜噜| 国产suv精品一区二区6| 国产精品人妻久久毛片高清无卡| 男女裸交无遮挡啪啪激情试看 | 亚洲中文字幕av无码区| 97夜夜澡人人双人人人喊| 亚洲va韩国va欧美va| 么公的好大好硬好深好爽视频| 国产爆乳无码视频在线观看| 国产精品福利2020久久| 一本加勒比hezyo无码人妻| 亚洲不卡中文字幕无码| 国产乱子伦农村叉叉叉| 久久人人超碰精品caoporen| 久久亚洲熟女cc98cm| 精品乱码一区二区三四区视频| 亚洲精品国产成人精品| a级大胆欧美人体大胆666| 久久久久人妻一区二区三区| 日韩人妻熟女中文字幕a美景之屋 高h纯肉无码视频在线观看 | 狠狠躁日日躁夜夜躁2020| 亚洲国产成人精品无码区花野真一| 国产精品一区在线观看你懂的| 暖暖视频日本在线观看| 国产精品亚洲а∨天堂网| 99爱在线精品视频免费观看 | 色一情一乱一伦| 亚洲国产高清av网站| 国内乱码一线二线三线| 国产亚洲视频中文字幕97精品 |