在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Kremen protein 1 (Kremen1), partial

Recombinant Mouse Kremen protein 1 (Kremen1), partial

  • 中文名稱：
    小鼠Kremen1重組蛋白
  • 貨號：
    CSB-YP860404MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Kremen1重組蛋白
  • 貨號：
    CSB-EP860404MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Kremen1重組蛋白
  • 貨號：
    CSB-EP860404MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Kremen1重組蛋白
  • 貨號：
    CSB-BP860404MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Kremen1重組蛋白
  • 貨號：
    CSB-MP860404MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Kremen1; Kremen; Kremen protein 1; Dickkopf receptor; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
  • 基因功能參考文獻：
    1. Kremen1 is expressed in prosensory cells during cochlear developme PMID: 27550540
    2. Dickkopf1 receptor Kremen1 is a bona fide dependence receptor, triggering cell death unless bound to its ligand. PMID: 26206087
    3. Kremen1 has a pro-apoptotic activity that is decreased upon Dkk1 binding PMID: 26206087
    4. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling PMID: 12050670
    5. Dkk1 and Kremen1 play roles in blastocyst activation and uterine receptivity during the window of implantation. PMID: 18068158
    6. Kremen may not be essential for Dkk1-mediated Wnt antagonism and Kremen may only play a role when cells express a high level of LRP5/6 PMID: 18502762
    7. This study provides the first genetic evidence for a functional interaction of Kremen proteins with Dkk1 as negative regulators of Wnt/beta-catenin signaling. PMID: 18505822

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 十八禁视频网站在线观看 | 国产亚洲精品aaaa片小说| 激情偷乱人成视频在线观看| 国产精品色拉拉| 亚洲人成无码网站在线观看| 国产精品 视频一区 二区三区| 欧美激情一区二区三区高清视频| 亚洲第一最快av网站| 国产成人午夜福利免费无码r| 国产一区二区三区美女| 国产成人亚洲综合色婷婷| 在线天堂资源www在线中文| 成在人线无码aⅴ免费视频| 蜜桃臀无码内射一区二区三区| 欧美变态另类牲交zozo| 国产美女亚洲精品久久久| 色偷偷色噜噜狠狠网站年轻人| 大陆熟妇丰满多毛xxxx| 国产人成无码视频在线| 五月色婷婷丁香无码三级| 无码视频在线观看| 18禁美女黄网站色大片免费看| 天堂最新版资源网| 久青草久青草视频在线观看| 开心久久婷婷综合中文字幕| 国产精品无码电影在线观看| 九九99久久精品在免费线18| 免费无码av一区二区三区| 国产精品永久免费视频| 亚洲国产精品嫩草影院永久| 日韩人妻ol丝袜av一二区| 久久国产成人午夜av影院| 中文午夜乱理片无码| 久久国产超碰女女av| 国产精品国产三级国产专区53| 国产xxxxx在线观看| 亚洲国产制服丝袜先锋| 成人免费无码大片a毛片| 亚洲欧美日韩中文无线码| 国产精品自在线一区| √天堂8资源中文在线|