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  4. Recombinant Mouse Interleukin-5 receptor subunit alpha (Il5ra), partial

Recombinant Mouse Interleukin-5 receptor subunit alpha (Il5ra), partial

  • 中文名稱：
    小鼠Il5ra重組蛋白
  • 貨號：
    CSB-YP011663MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Il5ra重組蛋白
  • 貨號：
    CSB-EP011663MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Il5ra重組蛋白
  • 貨號：
    CSB-EP011663MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Il5ra重組蛋白
  • 貨號：
    CSB-BP011663MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Il5ra重組蛋白
  • 貨號：
    CSB-MP011663MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Il5ra; Il5r; Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CD antigen CD125
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This is the receptor for interleukin-5. The alpha chain binds to IL5.
  • 基因功能參考文獻：
    1. SLy2 controls the antibody response to pneumococcal vaccine through an IL-5Ralpha-dependent mechanism in B-1 cells. PMID: 25330943
    2. Deglycosylated variant Il5ralpha has the same ligand binding affinity and biological activity as fully glycosylated IL5Ralpha, thus demonstrating a unique role for Asn196 glycosylation in IL5Ralpha function. PMID: 21770429
    3. Interleukin-5 receptor alpha chain expression and splicing during brain development in mice. PMID: 11811788
    4. Octamer Transcription Factor 2 (Oct2) augments the ability of activated B cells to differentiate to antibody-secreting plasma cells under T cell-dependent conditions through regulation of the gene encoding the interleukin 5 receptor alpha chain. PMID: 18250192
    5. We identified B-1 progenitors expressing low levels of IL-5 receptor alpha chain (IL-5Ralpha) and eosinophil progenitors expressing higher levels of IL-5Ralpha in the fetal liver PMID: 19428566
    6. The murine interleukin-5 receptor alpha chain pre-mRNA is alternatively spliced, resulting in soluble isoforms lacking the transmembrane coding region which do not complex with the IL-5R beta chain. PMID: 11425312

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  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed on eosinophils and basophils. Also on B-cells.
  • 數據庫鏈接：


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