在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Hyaluronidase-2 (Hyal2)

Recombinant Mouse Hyaluronidase-2 (Hyal2)

  • 中文名稱：
    小鼠Hyal2重組蛋白
  • 貨號：
    CSB-YP010919MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Hyal2重組蛋白
  • 貨號：
    CSB-EP010919MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Hyal2重組蛋白
  • 貨號：
    CSB-EP010919MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Hyal2重組蛋白
  • 貨號：
    CSB-BP010919MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Hyal2重組蛋白
  • 貨號：
    CSB-MP010919MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Hyal2Hyaluronidase-2; Hyal-2; EC 3.2.1.35; Hyaluronoglucosaminidase-2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    21-448
  • 氨基酸序列
    GELKPTAPPI FTGRPFVVAW NVPTQECAPR HKVPLDLRAF DVKATPNEGF FNQNITTFYY DRLGLYPRFD AAGTSVHGGV PQNGSLCAHL PMLKESVERY IQTQEPGGLA VIDWEEWRPV WVRNWQEKDV YRQSSRQLVA SRHPDWPSDR VMKQAQYEFE FAARQFMLNT LRYVKAVRPQ HLWGFYLFPD CYNHDYVQNW ESYTGRCPDV EVARNDQLAW LWAESTALFP SVYLDETLAS SVHSRNFVSF RVREALRVAH THHANHALPV YVFTRPTYTR GLTGLSQVDL ISTIGESAAL GSAGVIFWGD SEDASSMETC QYLKNYLTQL LVPYIVNVSW ATQYCSWTQC HGHGRCVRRN PSANTFLHLN ASSFRLVPGH TPSEPQLRPE GQLSEADLNY LQKHFRCQCY LGWGGEQCQR NYKGAAGN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
  • 基因功能參考文獻：
    1. Hyal2(-/-) mice have increased hyaluronan, which may promote endothelial-to-mesenchymal transition and proliferation of mesenchymal cells leading to congenital heart defects and heart failure. PMID: 28196902
    2. Hyal2-/- mice present craniofacial abnormalities, including submucosal cleft palate and incompletely penetrant cor triatriatum sinister with hearing loss. PMID: 28081210
    3. our data uncover a previously unsuspected mechanism of how hyaluronan and Hyal-2 control platelet generation. PMID: 27398974
    4. Removal of Hyal2 activity resulted in increased levels of hyaluronan creating a risk for cor triatriatum sinister. PMID: 26901790
    5. hyaluronidase 2 deficiency induces chronic thrombotic microangiopathy with hemolytic anemia in mice. PMID: 25934767
    6. HYAL2 plays a redundant role in the catalysis of megadalton HA to its 20 kDa intermediate during fertilization. PMID: 25232017
    7. Murine hyaluronidase 2 deficiency results in extracellular hyaluronan accumulation and severe cardiopulmonary dysfunction PMID: 23172227
    8. Hyal-2 enhancement of tumor necrosis factor-alpha-stimulated cytotoxicity in fibroblasts is blocked by Transforming growth factor-beta1. PMID: 11960552
    9. murine HYAL2 has a physiological activity in vivo that is relevant for craniovertebral bone formation, maintenance of plasma hyaluronan concentrations, and erythrocyte and platelet homeostasis. PMID: 18772348
    10. platelets and megakaryocytes contain only hyaluronidase 2 (HYAL2) but not HYAL1 PMID: 19443707

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Glycosyl hydrolase 56 family
  • 組織特異性：
    Widely expressed. In the brain, expressed during embryonic stages but expression decreases after birth and is barely detectable in adult brain.
  • 數據庫鏈接：


主站蜘蛛池模板： 人人妻人人玩人人澡人人爽| 肉感饱满中年熟妇日本| 又黄又粗又爽免费观看| 国产卡一卡二卡三卡免费| 免费无码午夜理论电影| 人妻少妇精品中文字幕av蜜桃| 国产一区二区在线视频| 97人洗澡从澡人人爽人人模| 影音先锋啪啪av资源网站| 男女无遮挡xx00动态图120秒| 国产v亚洲v天堂a无码| 亚洲成在人线免费观看| 亚洲不卡一卡2卡三卡4卡5卡| 18禁黄网站男男禁片免费观看| 国产亚洲精品久久久久久无几年桃 | 欧美另类bbbxxxxx另类| 国内精品人妻无码久久久影院蜜桃 | 亚洲精品久久久久久下一站| 欧美 国产 日产 韩国 在线| 四库影院永久国产精品地址 | 少妇人妻在线视频| 欧洲成人一区二区三区| 亚洲欧美日本久久综合网站| 日韩精品亚洲aⅴ在线影院| 97精品国产一区二区三区四区| 亚洲国产精华液网站w| 国产精品夜间视频香蕉| 男女爽爽午夜18污污影院| 日本熟妇色xxxxx欧美老妇| 浴室人妻的情欲hd三级国产 | 中文亚洲无线码49vv| 女厕厕露p撒尿八个少妇| 国内精品久久久久久中文字幕| 日韩精品无码中文字幕一区二区| av无码国产在线看免费网站| 久久久久久亚洲精品不卡| 国产成人精品综合在线观看| 四房播色综合久久婷婷| 992tv精品视频tv在线观看| 拍真实国产伦偷精品| 亚洲成a人片在线观看高清|