在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Histone deacetylase 11 (Hdac11)

Recombinant Mouse Histone deacetylase 11 (Hdac11)

  • 中文名稱：
    小鼠Hdac11重組蛋白
  • 貨號：
    CSB-YP010237MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Hdac11重組蛋白
  • 貨號：
    CSB-EP010237MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Hdac11重組蛋白
  • 貨號：
    CSB-EP010237MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Hdac11重組蛋白
  • 貨號：
    CSB-BP010237MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Hdac11重組蛋白
  • 貨號：
    CSB-MP010237MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Hdac11
  • Uniprot No.：
  • 別名：
    Hdac11; Histone deacetylase 11; HD11; EC 3.5.1.98
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-347
  • 氨基酸序列
    MPHATQLYQH VPEKRWPIVY SPRYNITFMG LEKLHPFDAG KWGKVINFLK EEKLLSDGML VEAREASEED LLVVHTRRYL NELKWSFVVA TITEIPPVIF LPNFLVQRKV LRPLRTQTGG TIMAGKLAVE RGWAINVGGG FHHCSSDRGG GFCAYADITL AIKFLFERVE GISRATIIDL DAHQGNGHER DFMGDKRVYI MDVYNRHIYP GDRFAKEAIR RKVELEWGTE DEEYLEKVER NVRRSLQEHL PDVVVYNAGT DVLEGDRLGG LSISPAGIVK RDEVVFRVVR AHDIPILMVT SGGYQKRTAR IIADSILNLH DLGLIGPEFP CVSAQNSGIP LLSCAVP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  • 基因功能參考文獻：
    1. HDAC11-suppression suppresses oxidative stress to reduce apoptosis and inflammation in Fructose-treated primary cardiomyocytes. PMID: 29655790
    2. Results demonstrate that HDAC11 is an important metabolic regulator. Mice that lack HDAC11 are protected from diet-induced obesity and fatty liver. PMID: 29958910
    3. our results indicate that HDAC11 would suppress myoblast differentiation via regulation of MyoD-dependent transcription. These findings suggest that HDAC11 is a novel critical target for controlling myoblast differentiation. PMID: 28927261
    4. we have been able to demonstrate a lineage-restricted overexpression of HDAC11 in neutrophils and committed neutrophil precursors and it appears to associate with the transcription machinery, possibly regulating the expression of inflammatory and migratory genes in neutrophils. Our results highlight a unique and novel role for HDAC11 PMID: 28550123
    5. our results indicate that the alcohol-induced responsiveness of Kupffer cells to gut-derived endotoxin, in part, is governed by miR-155 and HDAC11 PMID: 28584078
    6. HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production. PMID: 28550044
    7. HDAC11 appears to function as a negative regulator of myeloid-derived suppressor cells expansion/function in vivo. PMID: 25155994
    8. HDAC6, primarily a cytoplasmic protein, associates with HDAC11 and modulates the expression of IL-10 as a transcriptional activator. PMID: 24747960
    9. The HDAC11 transcript is a PDGF target; the HDAC11 mRNA abundance correlates inversely with proliferative status. PMID: 24047695
    10. Male gender and male hormones accelerate kidney ischemia reperfusion-induced decreases in expression and binding of HDAC11, resulting in an increase in PAI-1 expression. PMID: 23657855
    11. Role for HDAC11 in central nervous system histone deacetylation and the development of oligodendrocytes and neurons during postnatal development. PMID: 17893925
    12. HDAC11 negatively regulated expression of the gene encoding interleukin 10 in antigen-presenting cells. PMID: 19011628

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Histone deacetylase family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 丰满人妻熟妇乱又仑精品| 理论片87福利理论电影| 国产精品高清视亚洲中文| 手机看黄av免费网址| a∨在线视频播放| 国产精品高清网站| 一出一进一爽一粗一大视频| 一本色道av久久精品+网站| 天天av天天av天天透| 国产吃奶在线观看| 人妻 校园 激情 另类| 国产色在线 | 亚洲| 日韩成人无码毛片一区二区| 97熟女毛毛多熟妇人妻aⅴ| 野外做受三级视频| 毛色毛片免费观看| 99久久免费国产精品四虎| 男人边吃奶边做好爽免费视频| 欧美日韩色另类综合| 成人aa免费视频在线播放| 精品久久久久久777米琪桃花| 囯产精品一区二区三区线| 巨胸不知火舞露双奶头无遮挡| 欧美人与动牲交a欧美| 午夜无码片在线观看影院y| 国产乱了伦视频大全亚琴影院| 图片小说视频一区二区| 亚洲国产精品久久久久婷婷软件 | 国产成人人人97超碰超爽8| 亚洲gv永久无码天堂网| 久久99久久99久久综合| 亚洲熟妇少妇任你躁在线观看无码 | 在线观看国产精品乱码app| 天堂资源最新在线| yy111111少妇无码理论片| 亚洲人成77在线播放网站| 国产日韩一区二区三区在线观看| 黑人粗硬进入过程视频| 国产成+人+综合+亚洲欧美丁香花| 最新国产精品无码| 在线成人一区二区|