在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Histone-binding protein RBBP4 (Rbbp4)

  • 中文名稱:
    小鼠Rbbp4重組蛋白
  • 貨號:
    CSB-YP730675MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rbbp4重組蛋白
  • 貨號:
    CSB-EP730675MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rbbp4重組蛋白
  • 貨號:
    CSB-EP730675MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rbbp4重組蛋白
  • 貨號:
    CSB-BP730675MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rbbp4重組蛋白
  • 貨號:
    CSB-MP730675MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Rbbp4; Rbap48; Histone-binding protein RBBP4; Chromatin assembly factor 1 subunit C; CAF-1 subunit C; Chromatin assembly factor I p48 subunit; CAF-I 48 kDa subunit; CAF-I p48; Nucleosome-remodeling factor subunit RBAP48; Retinoblastoma-binding protein 4; RBBP-4; Retinoblastoma-binding protein p48
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-425
  • 氨基酸序列
    ADKEAAFDD AVEERVINEE YKIWKKNTPF LYDLVMTHAL EWPSLTAQWL PDVTRPEGKD FSIHRLVLGT HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK INHEGEVNRA RYMPQNPCII ATKTPSSDVL VFDYTKHPSK PDPSGECNPD LRLRGHQKEG YGLSWNPNLS GHLLSASDDH TICLWDISAV PKEGKVVDAK TIFTGHTAVV EDVSWHLLHE SLFGSVADDQ KLMIWDTRSN NTSKPSHSVD AHTAEVNCLS FNPYSEFILA TGSADKTVAL WDLRNLKLKL HSFESHKDEI FQVQWSPHNE TILASSGTDR RLNVWDLSKI GEEQSPEDAE DGPPELLFIH GGHTAKISDF SWNPNEPWVI CSVSEDNIMQ VWQMAENIYN DEDPEGSVDP EGQGS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
  • 基因功能參考文獻:
    1. ARMC12 promotes neuroblastoma progression through interaction with RBBP4. PMID: 30026490
    2. RbAp48 was identified as critical in the proliferation of hypopharyngeal carcinoma in both in vitro and in vivo experiments. PMID: 26376479
    3. RBBP4 is a regulator of histone deacetylation during oocyte maturation and deacetylation is required for bipolar spindle assembly through Aurora kinase C PMID: 25788661
    4. The most significant change was an age-related decline in RbAp48, a histone-binding protein that modifies histone acetylation. PMID: 23986399
    5. Studies indicate that estrogen deficiency initiates tissue-specific apoptosis in the exocrine gland cells through RbAp48 overexpression. PMID: 20635899
    6. Estrogen deficiency initiates p53-mediated apoptosis in the exocrine glands through Rbbp4 overexpression. PMID: 16581768
    7. Results report that transgenic expression of RbAp48 resulted in the development of autoimmune exocrinopathy resembling Sjogren's syndrome. PMID: 19015307

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    WD repeat RBAP46/RBAP48/MSI1 family
  • 組織特異性:
    Higher levels in brain, thymus, lung, spleen, kidney, testis, and ovary/uterus; lower levels in heart, liver, and muscle.
  • 數據庫鏈接:


主站蜘蛛池模板: 人妻少妇被粗大爽9797pw| 夜夜躁天天躁很很躁| 无码av免费一区二区三区| 国产成人av免费观看| 女人的天堂a国产在线观看| 最近中文字幕mv在线视频2018| 欧美老妇人与禽交| 午夜寂寞少妇aaa片毛片| 国产九九99久久99大香伊| 中文字幕 乱码 中文乱码视频| 亚洲国产精华液网站w| 久久无码av三级| 中文字幕丰满伦子无码| 久久精品青青草原伊人| 真人抽搐一进一出视频| 水蜜桃av无码| 免费人成在线视频无码| 一边捏奶一边高潮视频| 欧美黑人巨大xxxxx| 日本高清熟妇老熟妇| 国产乱子伦一区二区三区视频播放| 色中色成人导航| 国产产区一二三产区区别在线| 狼群社区www中文视频| 国产精品自在拍首页视频8| 人人妻人人澡人人爽久久av| 无码人妻视频一区二区三区| 亚洲欧洲精品a片久久99| 中文字幕亂倫免賛視頻| 精品无码av一区二区三区不卡| 俺也来俺也去俺也射| 午夜福利无遮挡十八禁视频| 欧美日产成人高清视频| 久久人妻少妇嫩草av无码专区 | 国产乱码一区二区三区| 欧美老妇与zozozo交| 欧美嫩交一区二区三区| 亚洲人成人影院在线观看| 香港三级精品三级在线专区| 久久久久蜜桃精品成人片| 玩50岁四川熟女大白屁股直播|