Recombinant Mouse Granzyme F (Gzmf)

中文名稱(chēng)：

小鼠Gzmf重組蛋白
貨號(hào)：

CSB-YP362539MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

小鼠Gzmf重組蛋白
貨號(hào)：

CSB-EP362539MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

小鼠Gzmf重組蛋白
貨號(hào)：

CSB-EP362539MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

小鼠Gzmf重組蛋白
貨號(hào)：

CSB-BP362539MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

小鼠Gzmf重組蛋白
貨號(hào)：

CSB-MP362539MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Gzmf
Uniprot No.：

P08883
別名：

Gzmf; Ccp4; Ctla-7; Ctla7Granzyme F; EC 3.4.21.-; C134; CTL serine protease 3; Cytotoxic cell protease 4; CCP4; Cytotoxic serine protease 3; MCSP3
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

21-248
氨基酸序列

IIGGHEVKPH SRPYMARVRF VKDNGKRHSC GGFLVQDYFV LTAAHCTGSS MRVILGAHNI RAKEETQQII PVAKAIPHPA YDDKDNTSDI MLLKLESKAK RTKAVRPLKL PRPNARVKPG HVCSVAGWGR TSINATQRSS CLREAQLIIQ KDKECKKYFY KYFKTMQICA GDPKKIQSTY SGDSGGPLVC NNKAYGVLTY GLNRTIGPGV FTKVVHYLPW ISRNMKLL
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
基因功能參考文獻(xiàn)：
1. Nna1 and CCP4 remove the C-terminal glutamate from substrates with two or more glutamates, whereas CCP6 requires four or more glutamates. CCP4 behaves as a promiscuous glutamase with little preference for chain length or neighboring amino acid composition PMID: 25416787
2. showed that GzmF impairs mitochondrial electron transport to abolish ATP generation; ATP decline may contribute to a failure of apoptosome formation, leading to caspase inactivation. PMID: 19644510
亞細(xì)胞定位：

Cytolytic granule.
蛋白家族：

Peptidase S1 family, Granzyme subfamily
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:14943

STRING: 10090.ENSMUSP00000022757

UniGene: Mm.457976