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  4. Recombinant Mouse Glutaredoxin domain-containing cysteine-rich protein 1 (Grxcr1)

Recombinant Mouse Glutaredoxin domain-containing cysteine-rich protein 1 (Grxcr1)

  • 中文名稱：
    小鼠Grxcr1重組蛋白
  • 貨號：
    CSB-YP687397MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Grxcr1重組蛋白
  • 貨號：
    CSB-EP687397MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Grxcr1重組蛋白
  • 貨號：
    CSB-EP687397MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Grxcr1重組蛋白
  • 貨號：
    CSB-BP687397MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Grxcr1重組蛋白
  • 貨號：
    CSB-MP687397MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Grxcr1
  • Uniprot No.：
  • 別名：
    Grxcr1; piGlutaredoxin domain-containing cysteine-rich protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-290
  • 氨基酸序列
    MLRRETKPES DRPRKVRFRI ASSHSGRVLK EVYEDGQAPG SLDSECASIC AIDGLSDSEG QQNGHIGSED NEQEKDQDNL LVLARTASEK AFGTRRVNIL SKNGTVRGVK YKVSAGQALF NNLTKVLQQP SADLEFDRVV IYTTCLRVVR TTFERCELVR KIFQNHRVKF EEKNIALNGD YGKELDERCR RVSEAPSLPV VFIDGHYLGG AEKILSMNES GELQDLLTKI ERVQHPHECP SCGGFGFLPC SVCHGSKMSV FRNCFTDAFK ALKCTACNEN GLQRCKNCTC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May play a role in actin filament architecture in developing stereocilia of sensory cells.
  • 基因功能參考文獻：
    1. Deafness in pirouette mutants is associated with loss of GRXCR1 function in modulating actin cytoskeletal architecture in the developing stereocilia of sensory hair cells. PMID: 20137774
  • 相關疾病：
    Defects in Grxcr1 are the cause of the pirouette (pi) phenotype which is characterized by vestibular defects and profound deafness with affected mice displaying abnormally thin and slightly shortened sterocilia.
  • 亞細胞定位：
    Cell projection, stereocilium. Cell projection, microvillus. Cell projection, kinocilium. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia.
  • 蛋白家族：
    GRXCR1 family
  • 組織特異性：
    In the inner ear, expressed predominantly in sensory hair cells and their stereocilia bundles with higher levels in outer hair cells (OHC) at P1 and in inner hair cells (IHC) at P5. At P1, expression is prominent in each row of stereocilia within bundles
  • 數據庫鏈接：


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