在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Gamma-aminobutyric acid receptor subunit alpha-6 (Gabra6), partial

Recombinant Mouse Gamma-aminobutyric acid receptor subunit alpha-6 (Gabra6), partial

  • 中文名稱：
    小鼠Gabra6重組蛋白
  • 貨號：
    CSB-YP009145MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gabra6重組蛋白
  • 貨號：
    CSB-EP009145MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gabra6重組蛋白
  • 貨號：
    CSB-EP009145MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gabra6重組蛋白
  • 貨號：
    CSB-BP009145MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gabra6重組蛋白
  • 貨號：
    CSB-MP009145MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Gabra6; Gabra-6Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 基因功能參考文獻：
    1. This study demonstrated that Ectopic Expression of alpha6 GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus. PMID: 26658866
    2. results indicate that in addition to the central role of homologous gamma-aminobutyric acid (GABA) A receptor subunit alpha 6-100R/Q (alpha1-101H) residue in benzodiazepine(BZ) binding this critical BZ binding site has a major impact on BZ binding kinetics PMID: 21163615
    3. ectopic expression of the GABA(A) receptor alpha6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition PMID: 12367600
    4. GABRA6 expression is regulated by NFI in cerebellar granule neurons PMID: 15466411
    5. Abnormal cerebellar P/Q-type VGCC activity results in a deficit of CGC-specific subtype(s) of GABA(A) receptors which may contribute to, or may be a consequence of the impaired cerebellar network signaling that occurs in cacna1a(tg) mice. PMID: 17614209
    6. some aspects of assembly, trafficking, targeting, and/or expression of extrasynaptic alpha6-containing GABA(A) receptors in cerebellar granule cells are selectively regulated by AMPA receptor-mediated signaling PMID: 17646167
    7. These findings suggest that the higher CNS depressant level achieved by ketamine may be the result of its selective actions on alpha6beta2/3delta receptors. PMID: 18480294
    8. We tested the hypothesis that homocysteine (Hcy) antagonizes the GABA(A) receptor and behaves as an excitotoxic neurotransmitter that causes blood brain barrier (BBB) permeability and vascular dementia. PMID: 18547546

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA6 sub-subfamily
  • 組織特異性：
    Only found in cerebellar granule cells.
  • 數據庫鏈接：


主站蜘蛛池模板： 青青草原综合久久大伊人精品| 亚洲精品久久久无码大桥未久| 国产无遮挡a片又黄又爽漫画| 长腿校花无力呻吟娇喘的视频| 久久成人影院精品777| 人妻免费一区二区三区最新| 免费能直接看黄的视频| 最近最新中文字幕高清免费| 男女猛烈xx00免费视频试看| 成人欧美一区二区三区在线| 亚洲 欧美 自拍 美腿 卡通| 国产播放隔着超薄丝袜进入| 久久妇女高潮喷水多| 羞羞色男人的天堂| 成人自慰女黄网站免费大全| 麻豆国产av超爽剧情系列| 国产乱人伦app精品久久| 亚洲国产精品久久久久婷婷软件| 超清精品丝袜国产自在线拍| 久久中文字幕无码专区| 亚洲欧美日韩综合一区| 成人精品动漫一区二区| 久久www免费人成看片入口| 久久久久国色av免费看| 无码人妻精品一区二区三区夜夜嗨| 国产成人av一区二区三区无码| 国产午夜精品av一区二区麻豆| 99久久人妻无码精品系列| 国产成人亚洲高清一区| 精品国产日韩亚洲一区| 美女无遮挡免费视频网站| 无码国产精品一区二区免费vr| 曰韩a∨无码一区二区三区| 热99re久久精品这里都是精品| 亚洲男女羞羞无遮挡久久丫| 九色精品国产成人综合网站| 亚洲欧洲日产国无高清码图片| 中国国语毛片免费观看视频| 香蕉久久av一区二区三区app| 人成午夜免费视频无码 | 动漫精品啪啪一区二区三区|