在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Gamma-aminobutyric acid receptor subunit alpha-4 (Gabra4), partial

Recombinant Mouse Gamma-aminobutyric acid receptor subunit alpha-4 (Gabra4), partial

  • 中文名稱：
    小鼠Gabra4重組蛋白
  • 貨號：
    CSB-YP887532MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gabra4重組蛋白
  • 貨號：
    CSB-EP887532MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gabra4重組蛋白
  • 貨號：
    CSB-EP887532MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gabra4重組蛋白
  • 貨號：
    CSB-BP887532MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gabra4重組蛋白
  • 貨號：
    CSB-MP887532MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Gabra4
  • Uniprot No.：
  • 別名：
    Gabra4Gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor subunit alpha-4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 基因功能參考文獻：
    1. These data suggest that pubertal synaptic pruning requires alpha4betadelta GABA-A receptors. PMID: 27136678
    2. Gabra4 KO CD4(+) cells produced increased cytokines. PMID: 28473323
    3. Rindings suggest that knock-out of the GABAR alpha4 subunit restores synaptic plasticity and spatial learning at puberty and is consistent with the concept that the dendritic alpha4betadelta GABARs which emerge at puberty selectively impair central nervous system plasticity. PMID: 26826007
    4. This study addressed the effects of AW on changes in the expression of Gabra4 and related genes that encode other subunits of GABAARs PMID: 26357588
    5. The alpha4 subunit-containing GABA A-receptors are required for the low dose, locomotor stimulatory effect of anesthetics. PMID: 24062179
    6. GABAA receptors in the mediodorsal thalamic nucleus (MD) modulate fear extinction. PMID: 24886120
    7. Increase in GABRA4 activity promotes hippocampal neurogenesis via nuclear factor of activated T cell (NFATc)4. PMID: 24948817
    8. This study demonistrated that alpha4-GABAARs contribute to nRT burst-mediated inhibition and that activity-dependent recruitment of eGABAARs dynamically influences the ventrobasal neuron tonic conductance during nRT tonic spike trains. PMID: 24027285
    9. alpha4 subunit expression strongly influences the pubertal increase of delta subunits at the plasma membrane, and that genetic deletion of alpha4 serves as a functional knock-down of delta-containing GABARs. PMID: 22418059
    10. findings show that emergence of alpha4betadelta GABARs at puberty impairs learning, an effect that can be reversed by a stress steroid PMID: 20299596
    11. alpha-4 subunit of the GABAA receptor is transcriptionally regulated PMID: 15265862
    12. Gamma-aminobutyric acid type A receptor alpha 4 subunit knockout mice are resistant to the amnestic effect of isoflurane. PMID: 19923508

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA4 sub-subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 成人aaa片一区国产精品| 亚洲 制服 丝袜 无码 在线| 国产在线精品一区在线观看| 天天摸夜夜摸夜夜狠狠摸| 玩弄人妻少妇500系列网址| 国产在线一区二区在线视频 | 国产精品久久久一区二区| 欧美506070老妇乱子伦| 久久久久国产精品人妻电影| 国产精品久久久久aaaa| 熟妇丰满多毛的大隂户| 十八禁真人啪啪免费网站 | 亚洲一区二区制服在线| 在线看免费无码av天堂的| 无码精品尤物一区二区三区| 中文字幕丰满孑伦无码精品| 国产精品成人一区二区不卡| 色噜噜狠狠色综合av| 扒开双腿疯狂进出爽爽爽| 中国xxxx做受视频| 久久精品道一区二区三区| 亚洲男女一区二区三区| 少妇高潮喷潮久久久影院| 国产亚洲熟妇在线视频| 日韩人妻无码中文字幕视频| 少妇私密会所按摩到高潮呻吟| 97无码免费人妻超级碰碰夜夜| 成年女人看片永久免费视频 | 免费1级做爰片在线观看爱| 人妻丰满熟妇av无码区乱| 色婷婷久久综合中文久久一本| 人妻少妇无码精品专区| 人妻在卧室被老板疯狂进入| 男女啪祼交视频| 久久精品囯产精品亚洲| 337p日本欧洲亚洲大胆在线| 国产高清av首播原创麻豆| 国产成人乱色伦区| 欧美在线精彩视频免费播放| 国产精品免费精品自在线观看| 午夜成人爽爽爽视频在线观看|