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  4. Recombinant Mouse GATA-type zinc finger protein 1 (Zglp1)

Recombinant Mouse GATA-type zinc finger protein 1 (Zglp1)

  • 中文名稱：
    小鼠Zglp1重組蛋白
  • 貨號：
    CSB-YP632278MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Zglp1重組蛋白
  • 貨號：
    CSB-EP632278MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Zglp1重組蛋白
  • 貨號：
    CSB-EP632278MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Zglp1重組蛋白
  • 貨號：
    CSB-BP632278MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Zglp1重組蛋白
  • 貨號：
    CSB-MP632278MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Zglp1; Glp1; GATA-type zinc finger protein 1; GATA-like protein 1; GLP-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-266
  • 氨基酸序列
    MEAAQAGDLT RRQELLAPPC LDTESLRKSR PPALEPGALR CLTPNIRSLW PTCQDSVSTA LPFLQEKEKG LPGSPSPATQ VLGSCWELMV IGMSDHLSMA RNPRGTQCPN LEISSATSPA SLQRRPRKQL NPRMGIEKVD PRFKGVTLEF QIQPDSSLQI VPTYSLPGRS CSQKLPASPS KALASPGSSE ALGPRRCASC RTQRTPLWRD AEDGTPLCNA CGIRYKKYGT RCSSCWLVPR KSIQPKRLCG RCGMSQDPHL SPTQEL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase.
  • 基因功能參考文獻：
    1. study provides a comprehensive multi-level (circuit, synaptic, and molecular) explanation of how food intake behavior and body weight are regulated by endogenous central GLP-1. PMID: 29056294
    2. data demonstrate an increase in number of pro-alpha cells and activation of the intra-islet GLP-1 system comprise a self-defense mechanism for enhancing beta cell survival to combat lipid overload, which is in part mediated by oxidative stress and inflammation. PMID: 25976560
    3. Findings indicate an essential role for VAMP2 in GLP-1 exocytosis from the GLUTag L cell in response to a variety of established secretagogues. PMID: 24356748
    4. GLP-1 and analogues may provide neuroprotective actions in ALS PMID: 22384126
    5. Loss of GLP-1 is associated with germ cell development during embryonic oogenesis. PMID: 21123517
    6. data identify GLP-1 as a critical nuclear repressor in somatic cells of the gonad that is required for germ cell development, and highlight the importance of somatic-germ cell interactions in the regulation of this critical process PMID: 16982049

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  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Specifically expressed in adult testis and ovary. Expressed at high levels in the somatic cells of the developing gonads, including Leydig cells in the testes and granulosa cells in the ovaries.
  • 數據庫鏈接：


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