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  4. Recombinant Mouse G-protein coupled receptor-associated sorting protein 1 (Gprasp1), partial

Recombinant Mouse G-protein coupled receptor-associated sorting protein 1 (Gprasp1), partial

  • 中文名稱：
    小鼠Gprasp1重組蛋白
  • 貨號：
    CSB-YP713169MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gprasp1重組蛋白
  • 貨號：
    CSB-EP713169MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gprasp1重組蛋白
  • 貨號：
    CSB-EP713169MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gprasp1重組蛋白
  • 貨號：
    CSB-BP713169MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gprasp1重組蛋白
  • 貨號：
    CSB-MP713169MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Gprasp1
  • Uniprot No.：
  • 別名：
    Gprasp1; Kiaa0443G-protein coupled receptor-associated sorting protein 1; GASP-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
  • 基因功能參考文獻：
    1. present the First low resolution solution structure of myostatin-free and myostatin-bound states of GASP-1 and GASP-2 PMID: 25657005
    2. Gasp-1 overexpression resulted in increased myostatin expression. PMID: 25277978
    3. GASP-1 and GASP-2 are important modulators of GDF-11 and MSTN activity in vivo. PMID: 24019467
    4. Overexpression of Gasp1 led to an increase in muscle mass observed not before day 15 of postnatal life. PMID: 23046573
    5. The pattern of behavioral deficits observed in GASP-1-deficient mice is coherent with current knowledge of the role of striatal G protein-coupled receptor(GPCR)s in acquisition/expression of skilled behavior and motivation. PMID: 21091868

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  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    GPRASP family
  • 組織特異性：
    Expressed in the brain, with higher expression in the hippocampus, hypothalamus and olfactory bulb.
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:67298

    UniGene: Mm.271980



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