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  4. Recombinant Mouse G kinase-anchoring protein 1 (Gkap1)

Recombinant Mouse G kinase-anchoring protein 1 (Gkap1)

  • 中文名稱：
    小鼠Gkap1重組蛋白
  • 貨號：
    CSB-YP862420MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gkap1重組蛋白
  • 貨號：
    CSB-EP862420MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gkap1重組蛋白
  • 貨號：
    CSB-EP862420MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gkap1重組蛋白
  • 貨號：
    CSB-BP862420MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gkap1重組蛋白
  • 貨號：
    CSB-MP862420MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Gkap1
  • Uniprot No.：
  • 別名：
    Gkap1; Gkap42; G kinase-anchoring protein 1; cGMP-dependent protein kinase-anchoring protein of 42 kDa
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-366
  • 氨基酸序列
    MASAVLSSVL TTASRFALLQ VDSGSGSDSE PGKGKGRSNG KSQTLGNKAT SNEKKREKRR KKKEQQQSEA NELRNLAFKK IPQKSSHSIC NVQHELSSPN PAQKESREEN WQEWRQKDEQ LTSEMFEADL EKALLLSKLE YEEHKQDYEN AETASTQTKG INKKDKRKNH QGKDKPVTVS LKDFQCEDHI SKKAEESNSA QTLSHDGGFF NRLEDDVHKI LIREKRREQL TEHNGTDNSP APEHNQEVGL KDGRIERLKL ELERKDAEIQ KLKAVITQWE AKYKEVKARN GQLLKMLQEG EMKDKAEILL QVDESQSIKN ELTVQVSSLH AALEQERSKV KVLQAELAKY QGGRKGKRNF EPDHCR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
  • 基因功能參考文獻：
    1. Data show that cGMP-dependent kinase (cGK-Ialpha) knockdown partially rescued TNF-alpha-induced decrease in 42-kDa cGMP-dependent protein kinase-anchoring protein (GKAP42) and impairment of insulin signals. PMID: 25586176
  • 亞細胞定位：
    Golgi apparatus.
  • 蛋白家族：
    GKAP1 family
  • 組織特異性：
    Predominantly expressed in testis. Expressed in the adipose tissue (at protein level). In the testis it is restricted to spermatocytes and early round spermatids. Also expressed in cardiac fibroblasts.
  • 數據庫鏈接：


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