在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Frizzled-7 (Fzd7), partial

Recombinant Mouse Frizzled-7 (Fzd7), partial

  • 中文名稱：
    小鼠Fzd7重組蛋白
  • 貨號(hào)：
    CSB-YP730721MO1
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Fzd7重組蛋白
  • 貨號(hào)：
    CSB-EP730721MO1
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Fzd7重組蛋白
  • 貨號(hào)：
    CSB-EP730721MO1-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Fzd7重組蛋白
  • 貨號(hào)：
    CSB-BP730721MO1
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Fzd7重組蛋白
  • 貨號(hào)：
    CSB-MP730721MO1
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Fzd7; Frizzled-7; Fz-7; mFz7
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Activation by WNT8 induces expression of beta-catenin target genes. Following ligand activation, binds to CCDC88C/DAPLE which displaces DVL1 from FZD7 and leads to inhibition of canonical Wnt signaling, activation of G-proteins by CCDC88C and triggering of non-canonical Wnt responses. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
  • 基因功能參考文獻(xiàn)：
    1. these data provide functional evidence of a crucial role for Wnt signalling, via the Fzd7 receptor, during homeostasis of the gastric epithelium. PMID: 28600348
    2. FZD7 transmits non-canonical Wnt signaling by interacting Wnt5A in the regulation of extracellular matrix expression. PMID: 28736081
    3. Fzd7 is enriched in Lgr5(+) stem cells and binds Wnt3 and Wnt2b. PMID: 25892522
    4. the Wnt receptor, frizzled-7, is a downstream target of miR-184, and delivery of miR-184 mimic inhibits Wnt signaling in the OIR retina. PMID: 25796186
    5. Fzd7 is a new partner of adherens junctional complex and represents a novel molecular switch for the control of vascular permeabilityvia activation of the Wnt-canonical pathway PMID: 24866384
    6. observed genetic interactions between Fz2 and Fz7 and five canonical and/or non-canonical signaling molecules: Dvl3, Wnt3a, Wnt11, Vangl2, and Wnt5a PMID: 23095888
    7. Data show that the Fzd7 receptor complex was associated with Galpha(s) and PI(3)K and these components were required for Wnt7a to activate the Akt/mTOR growth pathway in myotubes. PMID: 22179044

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor Fz/Smo family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 熟妇人妻中文字幕| 99久久国产综合精品五月天| 欧美真人做爰在线观看| 成人免费国产精品视频 | 国偷自产一区二区三区在线视频| 国产乱子伦在线一区二区| 久久不见久久见免费影院3| 免费国产a国产片高清| 窝窝午夜看片成人精品| 影音先锋啪啪av资源网站| 久久精品aⅴ无码中文字字幕蜜桃 午夜成人鲁丝片午夜精品 | 亚洲-av-无限看| 中文字幕乱码免费专区| 日本三级香港三级三级人!妇久| 国产欧美日韩精品a在线观看| 狠狠色成人综合网| 五十路熟妇强烈无码| 久久久亚洲欧洲日产国码aⅴ| 亚洲精品久久久蜜桃| 成人aa免费视频在线播放| 久久午夜私人影院| 十八禁无码免费网站| 色婷婷综合中文久久一本| 午夜性开放午夜性爽爽| 免费啪视频在线观看视频日本 | 少妇人妻综合久久中文字幕| 最新国产精品精品视频| 亚洲卡一卡二乱码新区仙踪| 久久久久99精品成人片直播| 天堂俺去俺来也www色官网| 免费人成网站在线视频| 老色鬼在线精品视频| 老熟女毛茸茸浓毛| 国产精品久久久久久无码五月| 国产乱辈通伦影片在线播放亚洲| 狠狠躁夜夜躁人人爽天天5| 亚洲 另类 日韩 制服 无码| 加勒比中文无码久久综合色| 欧美老妇交乱视频在线观看| 真实国产乱子伦对白视频不卡 | 中文字幕丰满伦子无码|