在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Extracellular matrix protein FRAS1 (Fras1), partial

Recombinant Mouse Extracellular matrix protein FRAS1 (Fras1), partial

  • 中文名稱：
    小鼠Fras1重組蛋白
  • 貨號：
    CSB-YP801931MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Fras1重組蛋白
  • 貨號：
    CSB-EP801931MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Fras1重組蛋白
  • 貨號：
    CSB-EP801931MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Fras1重組蛋白
  • 貨號：
    CSB-BP801931MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Fras1重組蛋白
  • 貨號：
    CSB-MP801931MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Fras1
  • Uniprot No.：
  • 別名：
    Fras1; Kiaa1500Extracellular matrix protein FRAS1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in extracellular matrix organization. Required for the regulation of epidermal-basement membrane adhesion responsible for proper organogenesis during embryonic development. Involved in brain organization and function.
  • 基因功能參考文獻：
    1. The close correlation between limb bud epidermal blistering, decreased Msx2 expression, and reduced ICD in the Fras1(rdf) hindlimb buds suggests that epithelium detachment from the mesenchyme may create a physical gap that interrupts the transmission of BMP, among other signals, resulting in soft tissue syndactyly. PMID: 26813283
    2. the role of Fras1 in development PMID: 24143185
    3. Targeted deletion of Fras1 in kidney podocytes circumvented skin blistering, renal agenesis, and early death. PMID: 22730198
    4. Report Fras1 up-regulation/Frem down-regulation in nephrons from mice with polycystic kidney disease and Frem2 mutations. PMID: 21993971
    5. The QBRICK, together with Fras1, defines the ability of BMs to bind integrin 81 through modulating the BM assembly of nephronectin, thereby regulating the integrin 81-mediated signals transmitted from the ureteric buds to the metanephric mesenchyme. PMID: 22613833
    6. Screened DNA from bl/bl mice and identified a premature termination of mouse Fras1. Thus, the bl mouse is a model for Fraser syndrome in humans. PMID: 12766769
    7. QBRICK/Frem1, Fras1, and Frem2 interactions at the basement membrane have roles in preventing Fraser syndrome-like defects PMID: 16880404
    8. Taken together, our findings indicate that besides a cooperative function with Fras1 in embryonic basement membranes, Frem1 can also act independently in processes related to epidermal differentiation. PMID: 17240369
    9. Study reports the immunofluorescence pattern of Frem3 and a comparative analysis of the spatiotemporal localization of all Fras1/Frem proteins during mouse embryonic development. PMID: 17251066
    10. Fras1 is not only essential as a component of a macromolecular complex for the extracellular stabilization of Frem2 but it is also required for its proper intracellular trafficking and export from embryonic epithelial cells. PMID: 17596926
    11. The localization pattern of Fras1 and Frem2 was indistinguishable, while both proteins along with Frem3 could be detected even in the absence of Frem1. PMID: 18563433
    12. Fras1 is expressed in the branching ureteric bud; renal agenesis occurs in homozygous Fras1 null mutant blebbed (bl) mice on a C57BL6J background. PMID: 18787044

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Defects in Fras1 are the cause of blebbed (bl) phenotype, which is characterized by blister formation, syndactyly, eyelid fusion and renal agenesis. Subepidermal blisters are predominantly formed in the head region around the eyes and at the distal part of the limbs. As development proceeds blisters that are initially transparent gradually become hemorrhagic and embryos die between E14.5 and E16.5.
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein; Extracellular side.
  • 蛋白家族：
    FRAS1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 人妻少妇精品视中文字幕国语| 无码中文av有码中文av| 亚洲精品国产av天美传媒| 精品国产一二三产品区别在哪| 亚洲熟妇av日韩熟妇av| 偷国产乱人伦偷精品视频| 无码熟妇人妻av在线影片| 内射巨臀欧美在线视频| 人妻老妇乱子伦精品无码专区| 国产又黄又大又粗视频| 疯狂撞击丝袜人妻| 欧美又粗又大又硬又长又爽视频 | 久久久久人妻精品一区三寸| 国产福利日本一区二区三区| 天天综合色天天综合色hd| 亚洲国产中文在线二区三区免| 亚洲乱亚洲乱妇无码| 日本视频免费高清一本18| 久久99精品国产99久久6不卡| 国产伦精品一区二区三区免费| 日韩插啊免费视频在线观看| 隔壁人妻被水电工征服| 无码人妻一区二区三区av| 国产l精品国产亚洲区久久| 久久精品亚洲男人的天堂| 国产欧美国日产高清| 内射后入在线观看一区| 国产v综合v亚洲欧美久久| 亚洲国产日韩一区三区| 免费无码av一区二区三区| 亚洲人成人网站色www| 非洲黑人性xxxx精品| 狠狠做五月深爱婷婷伊人| 天堂а√中文在线官网| 午夜成人爽爽爽视频在线观看 | 蜜臀av99无码精品国产专区| 欧美人与禽z0zo牲伦交| 青青草大香焦在线综合视频| 免费又黄又裸乳的视频| 潮喷大喷水系列无码久久精品| 日韩电影一区二区三区|