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  4. Recombinant Mouse Erythrocyte band 7 integral membrane protein (Stom)

Recombinant Mouse Erythrocyte band 7 integral membrane protein (Stom)

  • 中文名稱：
    小鼠Stom重組蛋白
  • 貨號：
    CSB-YP022862MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Stom重組蛋白
  • 貨號：
    CSB-EP022862MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Stom重組蛋白
  • 貨號：
    CSB-EP022862MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Stom重組蛋白
  • 貨號：
    CSB-BP022862MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Stom重組蛋白
  • 貨號：
    CSB-MP022862MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Stom; Epb7.2; Epb72; Erythrocyte band 7 integral membrane protein; Protein 7.2b; Stomatin
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-284
  • 氨基酸序列
    MSDKRQSSHV QSQRIPESFR ENSKTELGAC GWILVAASFF FVIITFPISI WICIKIVKEY ERVIIFRLGR ILQGGAKGPG LFFILPCTDS LIKVDMRTIS FDIPPQEVLT KDSVTISVDG VVYYRVQNAT LAVANITNAD SATRLLAQTT LRNALGTKNL SQILSDREEI AHHMQSTLDD ATDDWGIKVE RVEIKDVKLP VQLQRAMAAE AEAAREARAK VIAAEGEMNA SRALKEASMV ITESPAALQL RYLQTLTTIA AEKNSTIVFP LPVDMLQGIM GSNH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
  • 基因功能參考文獻：
    1. Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons. PMID: 22773952
    2. Dimerization of stomatin is crucial for the repression of acid-sensing ion channel 3 (ASIC3) activity. PMID: 22850675
    3. These observations suggest that stomatin may play important roles in astrocytes and other cells by interacting with Panx1 carboxyl terminal to limit channel opening. PMID: 22768083
    4. Provides evidence for a new structural form of stomatin. PMID: 19032151
    5. stomatin binds to and alters the gating of acid-sensing ion channels PMID: 15471860
    6. stomatin is required for normal mechanotransduction in a subpopulation of vertebrate sensory neurons PMID: 17942620

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  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle.
  • 蛋白家族：
    Band 7/mec-2 family
  • 組織特異性：
    Expressed in all sensory neurons of the dorsal root ganglia. In the CNS, expressed in many neurons of the spinal cord, medulla and pons. Expressed only in scattered neurons in the cortex, hippocampus, thalamus and basal ganglia. In the cerebellum, express
  • 數據庫鏈接：


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