在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse ETS domain-containing protein Elk-1 (Elk1)

Recombinant Mouse ETS domain-containing protein Elk-1 (Elk1)

  • 中文名稱：
    小鼠Elk1重組蛋白
  • 貨號：
    CSB-YP007603MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Elk1重組蛋白
  • 貨號：
    CSB-EP007603MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Elk1重組蛋白
  • 貨號：
    CSB-EP007603MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Elk1重組蛋白
  • 貨號：
    CSB-BP007603MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Elk1重組蛋白
  • 貨號：
    CSB-MP007603MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Elk1ETS domain-containing protein Elk-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-429
  • 氨基酸序列
    MDPSVTLWQF LLQLLREQGN GHIISWTSRD GGEFKLVDAE EVARLWGLRK NKTNMNYDKL SRALRYYYDK NIIRKVSGQK FVYKFVSYPE VAGCSTEDCP PQPEVSVTSA IAMAPATVHA GPGDTATGKP GTPKGAGMTG QGGLARSSRN EYMRSGLYST FTIQSLQPQP QPPIPPRPAS VLPNTTPAGV PAPASGSRST SPNPLEACLE AEEAGLPLQV ILTPPEAPNQ KSEELSLDPS FGHPQPPEVK VEGPKEELEA ARAGGFSSEA VKAEPEVSAS EGLLARLPAI LTENTAQVCG LSTSTTEITQ PQKGRKPRDL ELPLSPSLLG GQGPERTPGS GTSSGLQAPG PALTPSLLPT HTLTPVLLTP SSLPPSIHFW STLSPIAPRS PAKLSFQFPS SGSAQVHIPS ISVDGLSTPV VLSPGPQKP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation.
  • 基因功能參考文獻：
    1. the effects of vitamin C inhibiting the apo(a) expression were attenuated by ELK1siRNA and Tet2siRNA. These results suggested vitamin C down-regulate apo(a) expression via Tet2-dependent DNA demethylation in HepG2 cells PMID: 28192139
    2. These data reveal a novel role for Elk1 regulating ITGB6 expression and highlight how dysregulation of Elk1 can contribute to human disease. PMID: 26861876
    3. A role for Elk-1 in the transcriptional regulation of DUSP5 PMID: 26691724
    4. TNF-alpha modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1. PMID: 24121020
    5. novel GrB-EH(ITSN)-dependent pathogenic p38(MAPK)/Elk-1 signaling pathway involved in the poorly understood process of PL formation in severe PAH. PMID: 23893408
    6. Data show that formation of a Krupple-like factor KLF4, pELK-1, and histone de-acetylase 2 (HDAC2) multiprotein complex dependent on the SM22alpha G/C Repressor element. PMID: 22811558
    7. increased protein levels, phosphorylation and nuclear localization of Elk-1 observed in exon-1 and full-length Huntington's disease models could be a compensatory mechanism activated by striatal cells that contributes to neuroprotection PMID: 22372926
    8. Characterizes an orthologous rat short isoform derived from an in-frame downstream start codon. PMID: 11050086
    9. Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes PMID: 21846717
    10. Elk-1 phosphorylation downstream from extracellular signal-regulated kinase is a key molecular event involved in long-term neuronal and behavioral adaptations to cocaine. PMID: 21976515
    11. we aimed to identify the critical promoter regions of SPG4 gene and effects of Elk1 on SPG4 gene expression PMID: 21395583
    12. Results suggest a combined role for the transcription factors NF-kappaB and Elk-1 in the upregulation of AT(1)R in the CATH.a cell neuronal model. PMID: 20554912
    13. Data show that Elk-1 and Net do not contribute significantly to thymocyte development in the presence of SAP-1. PMID: 20554967
    14. The ability of Elk-1 to induce HO-1 promoter activity was independent of direct DNA binding, but rather occurred by interacting with the CCAAT/enhancer-binding protein-alpha (C/EBPalpha), which binds to DNA. PMID: 20348279
    15. Elk1 synergizes with C/EBP beta in the Ras-stimulated transactivation of the c-fos serum response element. PMID: 11151091
    16. H. pylori induction of villin in the stomach correlates with activation and cooperative binding of Elk-1 and the SRF to the proximal promoter of villin PMID: 15576363
    17. Elk-1 regulates telokin expression PMID: 16260603
    18. Data show that ERK1/2 regulates angiotensin II-dependent cell proliferation via cytoplasmic activation of RSK2 and nuclear activation of elk1. PMID: 16723511
    19. We suggest that LTD leads to SRF/Elk-1-regulated gene expression of immediate early transcription factors, which could in turn promote a second broader wave of gene expression. PMID: 16903857
    20. JNK1 and JNK2 differentially regulate TBP through Elk-1, controlling c-Jun expression and cell proliferation PMID: 17074809
    21. Results describe the role of Elk-1 in tumorigenesis, and show that the ElK-1 antisense oligonucleotide suppresses the tumorigenicity of human hepatocellular carcinoma cells. PMID: 17950002
    22. muscle differentiation is associated with a pattern of transcription factors that involves nuclear exclusion ELK1 and Forkhead box O and the increase in nuclear factor-kappaB DNA binding PMID: 17962350
    23. enhanced neuron-specific phosphorylation of Elk-1 at Ser383 is involved in cerebral cerebral hypoxic preconditioning of mice PMID: 19225881

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    ETS family
  • 組織特異性：
    Predominantly expressed in the brain, and to a lesser extent in the heart, liver and muscle.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲成a人v在线蜜臀| 亚洲日韩性欧美中文字幕| 国产欠欠欠18一区二区| 亚洲aⅴ天堂av天堂无码| 人妻少妇精品中文字幕av| 色噜噜狠狠色综合av| 亚洲已满18点击进入在线观看| 寂寞少妇做spa按摩无码| 国产男女猛烈无遮挡免费视频网站| 亚洲爆乳成av人在线蜜芽| 亚洲国产另类久久久精品黑人| 国产精品久久久久无码av| 99久久国产露脸精品竹菊传媒| 粗壮挺进人妻水蜜桃成熟漫画| 国产成人精品男人的天堂| 玩弄白嫩少妇xxxxx性| 亚洲人成黄网站69影院| 亚洲日韩在线中文字幕综合| 亚欧美日韩香蕉在线播放视频| wwww亚洲熟妇久久久久| 高中生粉嫩无套第一次| 国产精品福利视频一区| 国内a∨免费播放| 久久青青草原精品国产| 久久www成人影院| 久久久不卡国产精品一区二区| 国产精品99久久久久久宅男| 国产成人片无码免费视频软件 | 亚洲色大成网站www久久九九 | 国产成a人亚洲精品无码久久网| 欧美黑人又粗又大的性格特点| 在线va无卡无码高清| 无码写真精品永久福利在线| 99精品国产一区二区三区| 亚洲第一aaaaa片| 99久久99久久免费精品蜜桃| 国产免费一区二区三区不卡| 成年美女黄的视频网站| 男人的好看免费观看在线视频 | 国产av无码专区亚洲草草| 欧美丰腴丰满大屁股熟妇|