在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse EH domain-containing protein 2 (Ehd2)

  • 中文名稱:
    小鼠Ehd2重組蛋白
  • 貨號:
    CSB-YP803871MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Ehd2重組蛋白
  • 貨號:
    CSB-EP803871MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Ehd2重組蛋白
  • 貨號:
    CSB-EP803871MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Ehd2重組蛋白
  • 貨號:
    CSB-BP803871MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Ehd2重組蛋白
  • 貨號:
    CSB-MP803871MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ehd2EH domain-containing protein 2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-543
  • 氨基酸序列
    MFSWLKKGGA RGQRPEAIRT VTSSLKELYR TKLLPLEEHY RFGSFHSPAL EDADFDGKPM VLVAGQYSTG KTSFIQYLLE QEVPGSRVGP EPTTDCFVAV MHGETEGTVP GNALVVDPEK PFRKLNPFGN TFLNRFMCAQ LPNQVLESIS IIDTPGILSG AKQRVSRGYD FPAVLRWFAE RVDLIILLFD AHKLEISDEF SEAIGALRGH EDKIRVVLNK ADMVETQQLM RVYGALMWAL GKVVGTPEVL RVYIGSFWSQ PLLVPDNRRL FELEEQDLFR DIQGLPRHAA LRKLNDLVKR ARLVRVHAYI ISYLKKEMPT VFGKENKKKQ LILKLPVIFA KIQLEHHISP GDFPDCQKMQ ELLMAHDFTK FHSLKPKLLE ALDDMLAQDI AKLMPLLRQE ELESVEAGVQ GGAFEGTRMG PFVERGPDEA IEDGEEGSED DAEWVVTKDK SKYDEIFYNL APADGKLSGS KAKTWMVGTK LPNSVLGRIW KLSDVDRDGM LDDEEFALAS HLIEAKLEGH GLPTNLPRRL VPPSKRRQKG SAE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane.
  • 基因功能參考文獻:
    1. EHD2 may be cardioprotective as a dominant-negative EHD2 mutant sensitized cardiomyocytes to ischemic damage. Our findings highlight EHD2 as a potential pharmacologic target in the treatment of diseases with KATP channel trafficking defects PMID: 29133341
    2. The regulatory N-terminal residues and the EH domain keep the EHD2 dimer in an autoinhibited conformation in solution. By significantly advancing the use of infrared reflection-absorption spectroscopy, we demonstrate that EHD2 adopts an open conformation by tilting the helical domains upon membrane binding. PMID: 28223496
    3. The helical domain of EHD2 is inserted into the membrane.The N terminus domain regulates caveolar targeting of EHD2. PMID: 24508342
    4. Assembly of EHD2 stabilized and constrained caveolae to the plasma membrane to control turnover, and depletion of EHD2, resulting in endocytic and more dynamic and short-lived caveolae. PMID: 22323287
    5. The characterization of Fer1L5 and its interaction with EHD1 and EHD2 underscores the complex requirement of ferlin proteins and mediators of endocytic recycling for membrane trafficking events during myotube formation PMID: 21177873
    6. appears to connect endocytosis to the actin cytoskeleton through interactions of its N-terminal domain with membranes and its C-terminal EH domain with the novel EHBP1 protein PMID: 14676205

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, caveola; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
  • 蛋白家族:
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
  • 組織特異性:
    Detected in lung and adipocytes. Detected at lower levels in heart and skeletal muscle.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品nv久久久久久久久久| 熟妇人妻系列av无码一区二区| 国产三级精品三级在线专1| 综合图区亚洲欧美另类图片 | 精品乱码久久久久久中文字幕| 窝窝午夜色视频国产精品破| 亚洲精品无码专区在线播放| 中国性欧美videofree精品| 亚洲人午夜射精精品日韩| 丰满人妻无奈张开双腿av| 欧美大屁股流白浆xxxx| 亚洲午夜av久久久精品影院| 闺蜜张开腿让我爽了一夜| 伊人久久大香线蕉av仙人| 影音先锋人妻av中文字幕久久| 免费观看又色又爽又黄的崩锅| 一道久久爱综合久久爱| 一区二区三区无码免费看| 777午夜福利理伦电影网| 日本无码人妻精品一区二区蜜桃| 伊人蕉久中文字幕无码专区| 国产自偷自偷免费一区| 亚洲熟妇av一区| 天堂亚洲2017在线观看| 亚洲最新无码成av人| 无码精品人妻一区二区三区人妻斩| 日韩人妻一区二区三区免费| 国产精品成人3p一区二区三区| 伊人久久大香线蕉影院| 国产精品成人观看视频| 强制高潮18xxxx按摩| 日产精品一区2区卡四卡二卡| 小嫩妇好紧好爽再快视频| 朝鲜美女黑毛bbw| 中国丰满人妻videoshd| 国产情侣一区二区| 激情国产一区二区三区四区| 久久久久人妻精品区一三寸| 老司机免费的精品视频| 日产日韩亚洲欧美综合在线| 日本无遮挡真人祼交视频|