在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse E3 SUMO-protein ligase CBX4 (Cbx4)

  • 中文名稱:
    Recombinant Mouse E3 SUMO-protein ligase CBX4(Cbx4)
  • 貨號:
    CSB-YP004600MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse E3 SUMO-protein ligase CBX4(Cbx4)
  • 貨號:
    CSB-EP004600MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse E3 SUMO-protein ligase CBX4(Cbx4)
  • 貨號:
    CSB-EP004600MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse E3 SUMO-protein ligase CBX4(Cbx4)
  • 貨號:
    CSB-BP004600MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse E3 SUMO-protein ligase CBX4(Cbx4)
  • 貨號:
    CSB-MP004600MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Cbx4
  • Uniprot No.:
  • 別名:
    Cbx4; Pc2; E3 SUMO-protein ligase CBX4; EC 2.3.2.-; Chromobox protein homolog 4; E3 SUMO-protein transferase CBX4; Polycomb 2 homolog; Pc2; mPc2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-551
  • 氨基酸序列
    MELPAVGEHV FAVESIEKKR IRKGRVEYLV KWRGWSPKYN TWEPEENILD PRLLIAFQNR ERQEQLMGYR KRGPKPKPLV VQVPTFARRS NVLTGLQDSS ADNRAKLELG TQGKGQGHQY ELNSKKHHQY QPHSKERSGK PPPPGKSGKY YYQLNSKKHH PYQPDPKMYD LQYQGGHKEA PSPTCPDLGT KSHPPDKWAH GAAAKGYLGA VKPLGGGAGA PGKGSEKGPP NGMTPAPKEA VTGNGIGGKM KIVKNKNKNG RIVIVMSKYM ENGMQAVKIK SGEAAEGEAR SPSHKKRAAE ERHPQGDRTF KKAAGASEEK KAEVPCKRRE EEALVSGDAQ PQDLGSRKLS PTKEAFGEQP LQLTTKPDLL AWDPARSSHP PAHHHHHHHH HHHHHTVGLN LSHARKRCLS ETHGEREPCK KRLTARSIST PTCLGGSPVS EHPANVSPTA ASLPQPEVIL LDSDLDEPID LRCVKMRSDA GEPPSTLQVK PEAPAVAAVV APAPASEKPP AEAQEEPVEP LSEFKPFFGN IIITDVTANC LTVTFKEYVT V
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression.; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3). Plays a role in the lineage differentiation of the germ layers in embryonic development.
  • 基因功能參考文獻:
    1. The Cbx4 plays a crucial role in the p63-regulated program of epidermal differentiation, maintaining the epithelial identity and proliferative activity in KCs via repression of the selected nonepidermal lineage and cell cycle inhibitor genes. PMID: 26711500
    2. Data indicate an important role of chromobox homolog 4 protein CBX4 in production of high quality oocytes. PMID: 24280258
    3. Cbx4 is a crucial regulator for the generation and maintenance of the thymic epithelium and, hence, for thymocyte development. PMID: 23362346
    4. SUMO interaction motif 2 (SIM2) is crucial for many of the documented Pc2 functions, which converge on determining its E3 ligase activity. PMID: 20176810
    5. Our results suggest that Cbx4 functions as a SUMO E3 ligase for Dnmt3a and it might be involved in the functional regulation of DNA methyltransferases by promoting their SUMO modification. PMID: 17439403

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus speckle.
  • 組織特異性:
    Expressed in embryoid bodies.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲成av人片在线观看www| 精品国产午夜理论片不卡精品| 少妇高潮惨叫久久久久电影| 大伊香蕉精品视频在线| 少妇被爽到高潮动态图| 成人欧美一区二区三区1314| 成人做爰视频www网站小优视频| 亚洲国产成人久久久网站| 99久久九九社区精品| 国产一区二区三区精品视频| www亚洲精品少妇裸乳一区二区| 好紧好爽好湿别拔出来视频男男| 亚洲国产欧美一区二区好看电影| 国产97人妻人人做人碰人人爽| 免费观看又色又爽又湿的软件| 久久综合久久久久88| 国产精品96久久久久久| 亚洲精品卡2卡三卡4卡2卡乱码| 男女猛烈无遮挡免费视频app| 99re6热在线精品视频播放| 日本人妻丰满熟妇久久久久久| 中文字幕av高清片| 亚洲一码二码三码精华液| 色婷婷亚洲一区二区综合| 欧美肥婆姓交大片| 亚洲中文字幕无码爆乳app| 精品一区二区三人妻视频| 日本无卡码高清免费v| 无码午夜人妻一区二区三区不卡视频| 大地资源在线播放观看mv| 国产日产欧产精品精品| 欧美婷婷丁香五月社区 | 色噜噜噜亚洲男人的天堂| 国产成年无码v片在线| 久久精品女人天堂av | 性人久久网av| 久99视频精品免费观看福利| 亚洲第一无码av无码专区| 日本熟妇浓毛hdsex| 99er国产这里只有精品视频免费| 亚洲日韩看片无码超清|