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  4. Recombinant Mouse Doublesex- and mab-3-related transcription factor A2 (Dmrta2)

Recombinant Mouse Doublesex- and mab-3-related transcription factor A2 (Dmrta2)

  • 中文名稱：
    小鼠Dmrta2重組蛋白
  • 貨號：
    CSB-YP006973MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Dmrta2重組蛋白
  • 貨號：
    CSB-EP006973MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Dmrta2重組蛋白
  • 貨號：
    CSB-EP006973MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Dmrta2重組蛋白
  • 貨號：
    CSB-BP006973MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Dmrta2重組蛋白
  • 貨號：
    CSB-MP006973MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dmrta2
  • Uniprot No.：
  • 別名：
    Dmrta2; Dmrt5Doublesex- and mab-3-related transcription factor A2; Doublesex- and mab-3-related transcription factor 5
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-531
  • 氨基酸序列
    MELRSELPSV PGAATAAATA TGPPVASVAS VAAAAAAAAS LPVSVAGGLL RAPPLLLRAA EKYPRTPKCA RCRNHGVVSA LKGHKRYCRW KDCLCAKCTL IAERQRVMAA QVALRRQQAQ EENEARELQL LYGTAEGLAL AAANGIIPPR PAYEVFGSVC ATDGGGPGAG APAGSAGGAG GAEAKLQKFD LFPKTLLQAG RPDSPQPPPG KPLSPDGADS GPRTSSPEVR PGSGSENGDG ESFSGSPLAR ASKEAGGSCP GSAGAGGGGE EDSPGSSSPL GSESGSEADK EEAEAAPTPG LGGGPGPRQR TPLDILTRVF PGHRRGVLEL VLQGCGGDVV QAIEQVLNHH RGGLAAGLGP AAPLEKAAVS AAVEDAWPGR VEAAAAGGAG LPAPLQTGPT APPHHRPLLA GAMTPGALGS LSSRSAFSPL QPNASHFGAD AGAYPLGAPL GLSPLRLAYS AAAAHSRGLA FMAPYSTAGL VPTLGFRPPM DYAFSDLMRD RSAAAAAAVH KEPGYGGGLY GPMVNGTPEK Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in sexual development.
  • 基因功能參考文獻：
    1. there is a link between Dmrta2 modulation of Hes1 expression and the maintenance of neural progenitor cells during cortical development PMID: 28655839
    2. Dmrt5 is neurogenic, and reciprocally regulated by Lhx2; loss of either factor promotes gliogenesis. PMID: 29025924
    3. Dmrt5 is a novel Wnt-dependent transcription factor required for early cortical development PMID: 22923088
    4. data suggest that Dmrta2 plays pivotal roles in the early development of the telencephalon via the formation of the cortical hem, a source of Wnts, and also in the maintenance of neural progenitors as a downstream of the Wnt pathway PMID: 23056351
    5. Dmrt5 is an important player in ventral mesencephalic neural fate specification PMID: 21576465

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    DMRT family
  • 組織特異性：
    Expressed in adult brain and testis, as well as in embryonic ovary, kidney, heart, lung, stomach and brain.
  • 數據庫鏈接：


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