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  4. Recombinant Mouse Developmental pluripotency-associated protein 4 (Dppa4)

Recombinant Mouse Developmental pluripotency-associated protein 4 (Dppa4)

  • 中文名稱：
    小鼠Dppa4重組蛋白
  • 貨號：
    CSB-YP804939MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Dppa4重組蛋白
  • 貨號：
    CSB-EP804939MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Dppa4重組蛋白
  • 貨號：
    CSB-EP804939MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Dppa4重組蛋白
  • 貨號：
    CSB-BP804939MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Dppa4重組蛋白
  • 貨號：
    CSB-MP804939MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dppa4
  • Uniprot No.：
  • 別名：
    Dppa4Developmental pluripotency-associated protein 4; Embryonic stem cell-associated transcript 15-1 protein; ECAT15-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-296
  • 氨基酸序列
    METAGDKKWS AEEPKEEVEL QMSSQPSTAP AKAKATGKKQ KKSETDNGCK PKEGKPQDTE TPGQTRRKVP IPPIPEYLPP VNLIHRDVLR AWCQKKRVSS KGQKLDAYKR LLARAFPEQM LELRNVPDSA KDARLKTAHK KMKTEPGEES EVTVPLEMVP VPEEQIPALI DPPMLYEEVS TTVVTTPATE AVLASWARIA SNAKKYEAVP ADASSSSEVK GEMWCVVHGT SLPGNSRGWV RLQFHAGQAW VPDKKGKAIA LFLLPACTFP PPHLEDNMLC PKCVHKNKIL TKSLEG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic stem (ES) cells into a primitive ectoderm lineage.
  • 基因功能參考文獻：
    1. Results have identified a new family of pluripotency-related oncogenes consisting of DPPA2 and DPPA4. PMID: 23963736
    2. Study of expression and function of pluripotent markers such as Dppa2 and Dppa4 is likely to unveil new aspects of the regulation of pluripotency and germ line development in mammals. PMID: 16990585
    3. DPPA4 is a nuclear factor associated with active chromatin PMID: 17855347
    4. Thsi study identifies DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays. PMID: 18366076
    5. Dppa4 is completely dispensable for ES cell identity and germ cell development. Instead, loss of Dppa4 in mice results in late embryonic/perinatal death and striking skeletal defects with partial penetrance. PMID: 19332562

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  • 亞細胞定位：
    Nucleus. Note=Associated with transcriptionally active chromatin.
  • 組織特異性：
    Expressed in pluripotent embryonic cells, but not in differentiated somatic tissues.
  • 數據庫鏈接：


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